{"id":"86eec15d-1389-5320-b755-8316a97c5051","stable_key":"434e1e27-eb90-583a-956b-62472726ffba:parathyroid-loss-calcitriol-production","predicate":"loss_reduces","statement":"Thyroparathyroidectomy nearly abolished calcitriol production in low-calcium-fed rats; parathyroid extract restored it.","claim_class":"mechanistic","status":"source_derived_draft","evidence_grade":"ungraded","direction":"negative","is_public":true,"mechanism_event_id":"0fe7f4a9-2366-578c-b12a-9a49aaef737a","mechanism_event_label":"Hormonal support helps activate vitamin D during calcium restriction.","subject":{"id":"e162b0ab-1449-5471-b3c3-4638a0fa3a96","slug":"pth","display_name":"Parathyroid hormone / PTH","entity_type_key":"protein"},"object":{"id":"96b29e93-a2d1-56e7-84a3-2c5a61b4ee09","slug":"calcitriol-production","display_name":"Calcitriol production","entity_type_key":"cellular_process"},"evidence_count":1,"mechanism_event":{"id":"0fe7f4a9-2366-578c-b12a-9a49aaef737a","stable_key":"434e1e27-eb90-583a-956b-62472726ffba:parathyroid-loss-calcitriol-production-event","event_type":"biochemical_relationship","label":"Hormonal support helps activate vitamin D during calcium restriction.","description":"Thyroparathyroidectomy nearly abolished calcitriol production in low-calcium-fed rats; 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