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(2015). https://pubmed.ncbi.nlm.nih.gov/26227398/ DOI: 10.1142/s0192415x15500512","comparator":null,"unit":null,"notes":"","entity":null},{"dimension":"tissue_or_cell_type","value_text":"Transfected receptor reporter systems","comparator":null,"unit":null,"notes":"","entity":null}],"evidence":[{"id":"c42e1d4f-4ba9-56c4-b67b-d668e05c7d20","evidence_kind":"source_excerpt","locator":"Lines 662-673","start_line":662,"end_line":673,"excerpt":"### ceylon-ppard\nCinnamaldehyde activated the PPAR delta reporter in the TSA201 transfection experiment.\nCondition category: normal\nnutrient_topic: Ceylon cinnamon research collection; topical membership is not evidence of a direct dietary effect.\nplain_language: A receptor-controlled gene reporter increased; the exact binding mechanism remains unresolved.\norganism: Human-derived TSA201 host cells; mouse adipocytes\ntissue_or_cell_type: Transfected receptor reporter systems\nexperimental_model: Transient receptor reporters and 3T3-L1 expression assays\nlimitations: Reporter activation is not proof of direct receptor binding, a particular RXR isoform, vitamin A sparing, or human insulin sensitization.\nexposure: Purified cinnamaldehyde; reporter construct species/isoforms not resolved from abstract\nevidence_span: {\"source_cache\": \"artifacts/ceylon-research/26227398.abstract.txt\", \"locator\": \"Primary indexed abstract; zero-based, end-exclusive Unicode character offsets\", \"file_sha256\": \"6aa67e691d29bd1e0a13dd5e433b9b7aa2265ed650a21acfd66b79c715b7c9ea\", \"start_char\": 0, \"end_char\": 1580, \"text_sha256\": \"6aa67e691d29bd1e0a13dd5e433b9b7aa2265ed650a21acfd66b79c715b7c9ea\"}\n[ceylon-p26227398] Cinnamaldehyde Contributes to Insulin Sensitivity by Activating PPARδ, PPARγ, and RXR. 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