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[Loi 2019](https://pubmed.ncbi.nlm.nih.gov/31121222/)","status":"provisional","compartment":null,"participants":[{"entity":{"id":"01250874-17ba-5061-860c-cea7e909c706","slug":"saureus-bacilliredoxin-repair-system","display_name":"Staphylococcus aureus bacilliredoxin/bacillithiol/YpdA repair system","entity_type_key":"protein_set"},"role":"tested factor","stoichiometry":null,"state_label":"as reported","sequence_order":0,"notes":""},{"entity":{"id":"99be5e0e-3776-5ba5-92ed-71f517bfcda6","slug":"saureus-protein-s-thioallylation","display_name":"Protein S-thioallylation in Staphylococcus aureus","entity_type_key":"cellular_process"},"role":"measured outcome","stoichiometry":null,"state_label":"decrease","sequence_order":1,"notes":""},{"entity":{"id":"620cbc68-d6a2-5826-bed1-e13bc3dd895e","slug":"bacillithiol","display_name":"Bacillithiol / BSH","entity_type_key":"small_molecule"},"role":"electron-transfer thiol","stoichiometry":null,"state_label":"","sequence_order":2,"notes":""},{"entity":{"id":"5da94bf2-9480-57ee-9991-aeec6c4b881e","slug":"saureus-ypda","display_name":"Staphylococcus aureus bacillithiol-disulfide reductase / YpdA","entity_type_key":"protein"},"role":"reductase component","stoichiometry":null,"state_label":"","sequence_order":3,"notes":""}]},"contexts":[{"dimension":"evidence_access","value_text":"Primary indexed abstract reviewed; full methods, exact concentrations or species-specific attribution remain unextracted unless explicitly stated in the abstract or separately verified publisher text.","comparator":null,"unit":null,"notes":"","entity":null},{"dimension":"experimental_model","value_text":"Staphylococcus aureus biochemical repair evidence; abstract-level access.","comparator":null,"unit":null,"notes":"","entity":null},{"dimension":"interpretation_status","value_text":"Source-derived extraction of a fact-checked reference; access is explicit, not independent raw-data verification.","comparator":null,"unit":null,"notes":"","entity":null},{"dimension":"limitations","value_text":"Interpret only within the recorded preparation, exposure and comparator. 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No clinical efficacy, nutrient deficiency or unique molecular mediation is inferred.","comparator":null,"unit":null,"notes":"","entity":null},{"dimension":"plain_language","value_text":"The bacilliredoxin/bacillithiol/YpdA pathway reversed protein S-thioallylation in the reported biochemical study.","comparator":null,"unit":null,"notes":"","entity":null},{"dimension":"primary_references","value_text":"Staphylococcus aureus responds to allicin by global S-thioallylation - Role of the Brx/BSH/YpdA pathway and the disulfide reductase MerA to overcome allicin stress. | 2019 | DOI 10.1016/j.freeradbiomed.2019.05.018 | PMID 31121222 | https://pubmed.ncbi.nlm.nih.gov/31121222/ | https://doi.org/10.1016/j.freeradbiomed.2019.05.018","comparator":null,"unit":null,"notes":"","entity":null},{"dimension":"source_locator","value_text":"Reviewed reference lines 51-51; exact primary location described in quoted passage where extracted.","comparator":null,"unit":null,"notes":"","entity":null}],"evidence":[{"id":"c5ccc307-22b0-5a20-b6a7-fd6110f48304","evidence_kind":"source_excerpt","locator":"Lines 51-51","start_line":51,"end_line":51,"excerpt":"**Bacterial thiol systems differ.** Staphylococcus aureus uses bacillithiol rather than treating glutathione as its universal buffer. 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