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MPOD does not directly measure brain tissue.\nexposure: Lutein 10 mg + zeaxanthin 2 mg daily for one year\nevidence_span: {\"source_cache\": \"artifacts/lutein-research/29135938.fulltext.txt\", \"locator\": \"Primary full-text span; zero-based, end-exclusive Unicode character offsets\", \"file_sha256\": \"f60146e188d1a3093c572c3f637ebd659184f72727a75b35afd265b5ef0be71b\", \"start_char\": 21132, \"end_char\": 25480, \"text_sha256\": \"02d9398a25880c0ead3b3ef0ed91d12a98f837a8c8f89c141986dd926e1010a8\"}\n[lutein-p29135938] Effects of a Lutein and Zeaxanthin Intervention on Cognitive Function: A Randomized, Double-Masked, Placebo-Controlled Trial of Younger Healthy Adults. (2017). https://pubmed.ncbi.nlm.nih.gov/29135938/ DOI: 10.3390/nu9111246","model_system":"Small randomized double-masked placebo-controlled trial with biomarker-response analyses","directness":"author_interpretation","verification_status":"source_derived_draft","notes":"Exact curation-document quotation, not publisher quotation. Study references: [lutein-p29135938] Effects of a Lutein and Zeaxanthin Intervention on Cognitive Function: A Randomized, Double-Masked, Placebo-Controlled Trial of Younger Healthy Adults. (2017). https://pubmed.ncbi.nlm.nih.gov/29135938/ DOI: 10.3390/nu9111246","relationship":"supports","weight":1.0,"link_notes":"","source":{"id":"beef4241-6ebd-5b36-864c-6ef3ed7e61b8","stable_key":"import-cfa4bd86-d88d-555a-975c-68877bf00e0f","title":"Lutein: metabolism, signaling and nutrient connections (2026-09-17)","document_type":"imported_text","citation_label":"AI-assisted literature curation; primary study URLs and scope retained in the document and extraction. 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