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(2011). https://pubmed.ncbi.nlm.nih.gov/21245404/ DOI: 10.1167/iovs.10-5898","comparator":null,"unit":null,"notes":"","entity":null},{"dimension":"tissue_or_cell_type","value_text":"Foveal and parafoveal retina","comparator":null,"unit":null,"notes":"","entity":null},{"dimension":"trigger_kind","value_text":"nutrient_deficiency","comparator":null,"unit":null,"notes":"Imported condition classification; unverified.","entity":null}],"evidence":[{"id":"c9797819-bdb7-5c77-9790-43838584d35f","evidence_kind":"source_excerpt","locator":"Lines 437-448","start_line":437,"end_line":448,"excerpt":"### lutein-deprivation-protection\nThe foveal protection observed in controls was absent in xanthophyll-free animals.\nCondition category: nutrient_deficiency\nnutrient_topic: Lutein research collection; topical membership is not evidence of a direct dietary effect.\nplain_language: The central retina lost its relative protection in the challenge.\norganism: Rhesus macaque\ntissue_or_cell_type: Foveal and parafoveal retina\nexperimental_model: Dietary deprivation/repletion and controlled laser challenge\nlimitations: Extreme animal depletion and laser injury are not a defined human deficiency syndrome or ordinary screen exposure.\nexposure: Eight lifelong xanthophyll-deprived animals, n-3 intake strata; 22–28 weeks L or Z; 476-nm exposures\nevidence_span: {\"source_cache\": \"artifacts/lutein-research/21245404.abstract.txt\", \"locator\": \"Primary indexed abstract; zero-based, end-exclusive Unicode character offsets\", \"file_sha256\": \"74fa1a576a92084789e1a2d4afcd7c657e9ef2acaf9b0a6eaca46d543447ee2b\", \"start_char\": 0, \"end_char\": 1712, \"text_sha256\": \"74fa1a576a92084789e1a2d4afcd7c657e9ef2acaf9b0a6eaca46d543447ee2b\"}\n[lutein-p21245404] Nutritional manipulation of primate retinas, V: effects of lutein, zeaxanthin, and n-3 fatty acids on retinal sensitivity to blue-light-induced damage. 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