{"id":"72945689-a890-56a0-abcb-b3393dde114e","stable_key":"561b2b40-5b59-548f-a749-f357f7e2304c:monosodium-glutamate-cell-specific-rescue","predicate":"when_restored_selectively_rescues","statement":"Restoring Plcb2 only in bitter-receptor cells rescued bitter responses but not sweet or amino-acid responses.","claim_class":"mechanistic","status":"source_derived_draft","evidence_grade":"ungraded","direction":"context_dependent","is_public":true,"mechanism_event_id":"f3420f4c-791f-551c-aa77-45f36adfc168","mechanism_event_label":"Putting back machinery in the wrong cell type does not restore every signal.","subject":{"id":"45974bbf-1d69-5c63-a3c8-67f704a614c6","slug":"mouse-plcb2","display_name":"Mouse phospholipase C beta 2 / Plcb2","entity_type_key":"protein"},"object":{"id":"0b4326ec-57d8-5ea3-840c-1fc22071748d","slug":"mouse-bitter-cell-plcb2-rescue","display_name":"Mouse bitter-cell-specific Plcb2 rescue","entity_type_key":"cellular_process"},"evidence_count":1,"mechanism_event":{"id":"f3420f4c-791f-551c-aa77-45f36adfc168","stable_key":"561b2b40-5b59-548f-a749-f357f7e2304c:monosodium-glutamate-cell-specific-rescue-event","event_type":"observed_relationship","label":"Putting back machinery in the wrong cell type does not restore every signal.","description":"Restoring Plcb2 only in bitter-receptor cells rescued bitter responses but not sweet or amino-acid responses.","status":"provisional","compartment":null,"participants":[{"entity":{"id":"45974bbf-1d69-5c63-a3c8-67f704a614c6","slug":"mouse-plcb2","display_name":"Mouse phospholipase C beta 2 / Plcb2","entity_type_key":"protein"},"role":"subject","stoichiometry":null,"state_label":"","sequence_order":0,"notes":""},{"entity":{"id":"0b4326ec-57d8-5ea3-840c-1fc22071748d","slug":"mouse-bitter-cell-plcb2-rescue","display_name":"Mouse bitter-cell-specific Plcb2 rescue","entity_type_key":"cellular_process"},"role":"target","stoichiometry":null,"state_label":"","sequence_order":1,"notes":""},{"entity":{"id":"2952387b-d69b-5530-a976-a875ad008226","slug":"monosodium-glutamate","display_name":"Monosodium L-glutamate","entity_type_key":"small_molecule"},"role":"context_participant","stoichiometry":null,"state_label":"","sequence_order":2,"notes":""},{"entity":{"id":"7da684a4-2641-5bc6-93ae-8c6aa384e487","slug":"glutamate","display_name":"L-Glutamate","entity_type_key":"small_molecule"},"role":"context_participant","stoichiometry":null,"state_label":"","sequence_order":3,"notes":""},{"entity":{"id":"0ae3ccb3-32a3-5fe5-b199-e8499888b774","slug":"mouse-gpcr-taste-perception","display_name":"Mouse sweet, bitter and umami taste responses","entity_type_key":"cellular_process"},"role":"context_participant","stoichiometry":null,"state_label":"","sequence_order":4,"notes":""}]},"contexts":[{"dimension":"availability_state","value_text":"machinery_impairment","comparator":null,"unit":null,"notes":"Imported condition classification; 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