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added PLP enhanced the measured activity.\nCondition category: normal\nnutrient_topic: Vitamin B6 research collection; topical membership is not evidence of a direct dietary effect.\nplain_language: B6 cofactor supports this monoamine-producing step.\norganism: Human DDC expressed in monkey COS cells\ntissue_or_cell_type: COS-cell expression system\nexperimental_model: Human DDC expressed in monkey COS cells; enzyme assays\nlimitations: An expression-system response is not proof that supplements increase brain monoamines.\nexposure: PLP addition to transfected COS-cell enzyme incubations.\n[sumi-1990-ddc] Characterization of recombinant human aromatic L-amino acid decarboxylase expressed in COS cells (1990). https://doi.org/10.1111/j.1471-4159.1990.tb04601.x DOI: 10.1111/j.1471-4159.1990.tb04601.x","model_system":"Human DDC expressed in monkey COS cells; enzyme assays","directness":"author_interpretation","verification_status":"source_derived_draft","notes":"Exact curation-document quotation, not publisher quotation. 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