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(2017). https://pubmed.ncbi.nlm.nih.gov/29046261/ DOI: 10.1016/j.metabol.2017.08.006","comparator":null,"unit":null,"notes":"","entity":null},{"dimension":"tissue_or_cell_type","value_text":"Subcutaneous adipocytes in culture","comparator":null,"unit":null,"notes":"","entity":null}],"evidence":[{"id":"dfad806c-a7d9-5268-b724-21b85b122f1d","evidence_kind":"source_excerpt","locator":"Lines 532-543","start_line":532,"end_line":543,"excerpt":"### ceylon-hsl\nCinnamaldehyde increased HSL phosphorylation in primary mouse adipocytes.\nCondition category: normal\nnutrient_topic: Ceylon cinnamon research collection; topical membership is not evidence of a direct dietary effect.\nplain_language: A fat-handling enzyme changed its phosphorylation state.\norganism: Mouse\ntissue_or_cell_type: Subcutaneous adipocytes in culture\nexperimental_model: Primary adipocyte signaling with inhibitor and knockout experiments\nlimitations: Cell thermogenesis is not a measured increase in whole-person energy expenditure or proven weight loss.\nexposure: Acute and chronic purified cinnamaldehyde exposure\nevidence_span: {\"source_cache\": \"artifacts/ceylon-research/29046261.abstract.txt\", \"locator\": \"Primary indexed abstract; zero-based, end-exclusive Unicode character offsets\", \"file_sha256\": \"c0e0bba821363dc1d8ecdd40d3957b7d48778605b0d72bcf9016a26466cb2aac\", \"start_char\": 0, \"end_char\": 1763, \"text_sha256\": \"c0e0bba821363dc1d8ecdd40d3957b7d48778605b0d72bcf9016a26466cb2aac\"}\n[ceylon-p29046261] Cinnamaldehyde induces fat cell-autonomous thermogenesis and metabolic reprogramming. 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