{"id":"70102544-00ca-549f-a214-920c73983195","stable_key":"56f1d914-e7da-595a-af69-c217b2b47407:l-phenylalanine-gpr142-dispensability","predicate":"is_not_required_for","statement":"Phenylalanine-associated glucose-tolerance improvement persisted in Gpr142-knockout mice, and its modest islet insulin response was not significantly different between knockout and wild-type mice.","claim_class":"mechanistic","status":"source_derived_draft","evidence_grade":"ungraded","direction":"neutral","is_public":true,"mechanism_event_id":"f8b6d577-3041-585b-9cb3-8e5cee2d32a6","mechanism_event_label":"A receptor that responds in a dish may not be essential for the overall response.","subject":{"id":"a1317efc-1f28-5b59-be4d-1f9b051120af","slug":"mouse-gpr142","display_name":"Mouse Gpr142","entity_type_key":"protein"},"object":{"id":"c2976ad3-8393-58de-ae7d-c1567b6851ab","slug":"mouse-phe-glucose-response","display_name":"Mouse glucose-tolerance response to phenylalanine","entity_type_key":"cellular_process"},"evidence_count":1,"mechanism_event":{"id":"f8b6d577-3041-585b-9cb3-8e5cee2d32a6","stable_key":"56f1d914-e7da-595a-af69-c217b2b47407:l-phenylalanine-gpr142-dispensability-event","event_type":"observed_relationship","label":"A receptor that responds in a dish may not be essential for the overall response.","description":"Phenylalanine-associated glucose-tolerance improvement persisted in Gpr142-knockout mice, and its modest islet insulin response was not significantly different between knockout and wild-type mice.","status":"provisional","compartment":null,"participants":[{"entity":{"id":"a1317efc-1f28-5b59-be4d-1f9b051120af","slug":"mouse-gpr142","display_name":"Mouse Gpr142","entity_type_key":"protein"},"role":"subject","stoichiometry":null,"state_label":"","sequence_order":0,"notes":""},{"entity":{"id":"c2976ad3-8393-58de-ae7d-c1567b6851ab","slug":"mouse-phe-glucose-response","display_name":"Mouse glucose-tolerance response to phenylalanine","entity_type_key":"cellular_process"},"role":"target","stoichiometry":null,"state_label":"","sequence_order":1,"notes":""},{"entity":{"id":"190407ad-0219-54b5-b05f-7c75f3895ca6","slug":"l-phenylalanine","display_name":"L-Phenylalanine","entity_type_key":"small_molecule"},"role":"context_participant","stoichiometry":null,"state_label":"","sequence_order":2,"notes":""}]},"contexts":[{"dimension":"availability_state","value_text":"machinery_impairment","comparator":null,"unit":null,"notes":"Imported condition classification; 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