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It establishes where the zinc and the coenzyme sit; it is not a human kinetic measurement.","comparator":null,"unit":null,"notes":"","entity":null},{"dimension":"nutrient_topic","value_text":"Alcohol research collection; topical membership is not evidence of a direct clinical effect, and ethanol is recorded separately from the acetaldehyde it becomes.","comparator":null,"unit":null,"notes":"","entity":{"slug":"ethanol","display_name":"Ethanol","entity_type_key":"drug"}},{"dimension":"organism","value_text":"Horse enzyme","comparator":null,"unit":null,"notes":"","entity":null},{"dimension":"plain_language","value_text":"The zinc that does the chemistry sits at the bottom of a deep slot, far from the surface.","comparator":null,"unit":null,"notes":"","entity":null},{"dimension":"primary_references","value_text":"[alcohol-p4365379] Structure of liver alcohol dehydrogenase at 2.9-angstrom resolution. 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It establishes where the zinc and the coenzyme sit; it is not a human kinetic measurement.\nexposure: Inhibitor-bound and coenzyme-bound states\nevidence_span: {\"source_cache\": \"artifacts/alcohol-research/4365379.abstract.txt\", \"locator\": \"Indexed abstract; zero-based, end-exclusive Unicode character offsets\", \"file_sha256\": \"857dc9a65cac403f6591e0f33ea1bd3295f4a997274a26c362a3f392dbe9c987\", \"start_char\": 0, \"end_char\": 912, \"text_sha256\": \"857dc9a65cac403f6591e0f33ea1bd3295f4a997274a26c362a3f392dbe9c987\"}\n[alcohol-p4365379] Structure of liver alcohol dehydrogenase at 2.9-angstrom resolution. (1973). https://pubmed.ncbi.nlm.nih.gov/4365379/ DOI: 10.1073/pnas.70.8.2439","model_system":"X-ray crystallography of horse liver alcohol dehydrogenase at 2.9 angstrom","directness":"author_interpretation","verification_status":"source_derived_draft","notes":"Exact curation-document quotation, not publisher quotation. 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