{"id":"6d47d223-0c52-5e7f-9576-50d4c94f5a72","stable_key":"33bef151-bdc7-5892-aff6-0345ab149739:natto-food-carries-vitamin-k2","predicate":"contains","statement":"Natto food contains vitamin K2, and one 50 g pack typically carries 1,400 to 2,000 FU of nattokinase activity with a reported range of 600 to 3,290 FU per pack.","claim_class":"mechanistic","status":"source_derived_draft","evidence_grade":"ungraded","direction":"positive","is_public":true,"mechanism_event_id":"b466154f-24ad-5ac6-9c82-ffdcab9852d8","mechanism_event_label":"Natto food contains vitamin K2, and one 50 g pack typically carries 1,400 to 2,000 FU of nattokinase activity with a reported range of 600 to 3,290 FU per pack.","subject":{"id":"b7d0177d-170d-5ea4-995f-eec6760f640e","slug":"natto","display_name":"Natto, fermented soybean food","entity_type_key":"botanical"},"object":{"id":"a3ff2a7b-69f3-5098-8fac-fb8d7668397b","slug":"menaquinone-7","display_name":"Menaquinone-7 / MK-7","entity_type_key":"small_molecule"},"evidence_count":1,"mechanism_event":{"id":"b466154f-24ad-5ac6-9c82-ffdcab9852d8","stable_key":"33bef151-bdc7-5892-aff6-0345ab149739:natto-food-carries-vitamin-k2-event","event_type":"observed_intervention","label":"Natto food contains vitamin K2, and one 50 g pack typically carries 1,400 to 2,000 FU of nattokinase activity with a reported range of 600 to 3,290 FU per pack.","description":"Fermented soybean food","status":"provisional","compartment":null,"participants":[{"entity":{"id":"b7d0177d-170d-5ea4-995f-eec6760f640e","slug":"natto","display_name":"Natto, fermented soybean food","entity_type_key":"botanical"},"role":"acting component","stoichiometry":null,"state_label":"","sequence_order":0,"notes":""},{"entity":{"id":"a3ff2a7b-69f3-5098-8fac-fb8d7668397b","slug":"menaquinone-7","display_name":"Menaquinone-7 / MK-7","entity_type_key":"small_molecule"},"role":"component the finding is about","stoichiometry":null,"state_label":"","sequence_order":1,"notes":""}]},"contexts":[{"dimension":"duration","value_text":"Not applicable","comparator":null,"unit":null,"notes":"","entity":null},{"dimension":"evidence_access","value_text":"EFSA Journal opinion retrieved and read in full during this curation. Quoted figures are from the opinion text and its specification tables.","comparator":null,"unit":null,"notes":"","entity":null},{"dimension":"experimental_model","value_text":"Food composition","comparator":null,"unit":null,"notes":"","entity":null},{"dimension":"exposure","value_text":"Natto, 50 g portion","comparator":null,"unit":null,"notes":"","entity":null},{"dimension":"limitations","value_text":"Whole fermented soybeans also carry poly-gamma-glutamate, soy protein, peptides and live fermentation organisms. A typical pack is close in nattokinase activity to a 2,000 FU supplement capsule, which makes the vitamin K2 content the sharpest difference between them.","comparator":null,"unit":null,"notes":"","entity":null},{"dimension":"organism","value_text":"Food composition","comparator":null,"unit":null,"notes":"","entity":null},{"dimension":"plain_language","value_text":"Natto food contains vitamin K2, and one 50 g pack typically carries 1,400 to 2,000 FU of nattokinase activity with a reported range of 600 to 3,290 FU per pack.","comparator":null,"unit":null,"notes":"","entity":null},{"dimension":"primary_references","value_text":"Safety of fermented soybean extract NSK-SD as a novel food. (2016) DOI: 10.2903/j.efsa.2016.4541 Not indexed in PubMed.","comparator":null,"unit":null,"notes":"","entity":null},{"dimension":"route","value_text":"In vivo, oral","comparator":null,"unit":null,"notes":"","entity":null},{"dimension":"tissue","value_text":"Fermented soybean food","comparator":null,"unit":null,"notes":"","entity":null}],"evidence":[{"id":"c5f32f88-075d-5bce-a6c8-123896fc62cf","evidence_kind":"source_excerpt","locator":"Lines 1346-1346","start_line":1346,"end_line":1346,"excerpt":"Natto food contains vitamin K2, and one 50 g pack typically carries 1,400 to 2,000 FU of nattokinase activity with a reported range of 600 to 3,290 FU per pack.","model_system":"Food composition","directness":"reported_statement","verification_status":"source_derived_draft","notes":"","relationship":"supports","weight":1.0,"link_notes":"","source":{"id":"41cb127c-1c23-53aa-b7d0-5ec7f6fa3c99","stable_key":"import-33bef151-bdc7-5892-aff6-0345ab149739","title":"Nattokinase: what the purified enzyme cleaves, what survives being eaten, and the gap between the two (2026-09-23)","document_type":"imported_text","citation_label":"Original AI-assisted curation built from a supplied entity-first document of 105 entities and 129 claims. Every reference in that document was resolved against live PubMed with its abstract read and its DOI cross-checked on 2026-09-23, and the EFSA novel-food opinion was retrieved and read in full. That check corrected two PMIDs that pointed at unrelated papers, two DOIs, and two papers recorded as carrying no erratum that do carry one; it also reversed three findings the supplied document had stated backwards. Two papers carry a published correction, recorded as such and not as a retraction. Three sources are not indexed in PubMed and are cited by what they have. Laboratory lineages are recorded, so the four papers from one group, the three from another and the two readings of a single applicant dossier cannot be counted as separate lines of support. Study-specific doses, units, populations and limitations retained; activity units are never converted between systems. Not publisher full text.","file_path":"","sha256":"34fc46e0e849d06bfa13cb099a79b50679dd6fd0de8a5a0575326afdde3259c1","revision_id":"efd063e6-e982-5f6e-a4b8-6f2ffe4185ce","review_status":"unverified_draft","notes":""}}],"relations":[],"conflicts":[],"corrections":[],"research":null}