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(2014). https://pubmed.ncbi.nlm.nih.gov/24880340/ DOI: 10.1038/ng.2996","comparator":null,"unit":null,"notes":"","entity":null},{"dimension":"tissue_or_cell_type","value_text":"Erythroblasts and hepatic iron regulation","comparator":null,"unit":null,"notes":"","entity":null}],"evidence":[{"id":"dc054a84-a92f-5f21-9fb3-ecea9b726fca","evidence_kind":"source_excerpt","locator":"Lines 810-821","start_line":810,"end_line":821,"excerpt":"### iron-epo-erfe\nErythroblasts produced erythroferrone in response to erythropoietin.\nCondition category: normal\nnutrient_topic: Iron research collection; topical membership is not evidence of a direct dietary effect.\nplain_language: Red-cell production sends a hormonal request for more available iron.\norganism: Mice\ntissue_or_cell_type: Erythroblasts and hepatic iron regulation\nexperimental_model: Hemorrhage, erythropoietin response and gene deletion\nlimitations: Stress erythropoiesis and mouse overload mechanisms; the author correction (PMID 32107478; https://doi.org/10.1038/s41588-019-0548-y) corrects swapped human FAM132B and HPRT primer labels in Supplementary Table 2.\nexposure: Blood loss, EPO stimulation and Erfe deletion; thalassemia model\nevidence_span: {\"source_cache\": \"artifacts/iron-research/24880340.abstract.txt\", \"locator\": \"Exact primary indexed abstract; zero-based, end-exclusive Unicode character offsets\", \"file_sha256\": \"1e290e3082fe90ef8ef538ec8d5151082e3d38672abfba19731ea158957fcc54\", \"start_char\": 0, \"end_char\": 738, \"text_sha256\": \"1e290e3082fe90ef8ef538ec8d5151082e3d38672abfba19731ea158957fcc54\"}\n[iron-p24880340] Identification of erythroferrone as an erythroid regulator of iron metabolism. 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