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It does not by itself explain agonist efficacy differences.\nexposure: Antagonist-bound receptor crystallography\nevidence_span: {\"source_cache\": \"artifacts/thc-research/27768894.abstract.txt\", \"locator\": \"Indexed abstract; zero-based, end-exclusive Unicode character offsets\", \"file_sha256\": \"eca46f11c563fdc4265930c57c7d856782d2130b77721d8470e779a3efaf6cc1\", \"start_char\": 0, \"end_char\": 1042, \"text_sha256\": \"eca46f11c563fdc4265930c57c7d856782d2130b77721d8470e779a3efaf6cc1\"}\n[thc-p27768894] Crystal Structure of the Human Cannabinoid Receptor CB1. (2016). https://pubmed.ncbi.nlm.nih.gov/27768894/ DOI: 10.1016/j.cell.2016.10.004","model_system":"X-ray crystallography of the human CB1 receptor","directness":"author_interpretation","verification_status":"source_derived_draft","notes":"Exact curation-document quotation, not publisher quotation. Study references: [thc-p27768894] Crystal Structure of the Human Cannabinoid Receptor CB1. 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