{"id":"661e4f52-723f-541c-a3ef-2e0b847f6667","stable_key":"6cdb37aa-8998-5ea8-829d-4f995caf98fc:l-carnitine-microbial-coculture","predicate":"enables","statement":"Adding E. timonensis in coculture completed the carnitine-to-TMA conversion using other microbes' gamma-butyrobetaine production.","claim_class":"mechanistic","status":"source_derived_draft","evidence_grade":"ungraded","direction":"context_dependent","is_public":true,"mechanism_event_id":"d063f31d-0412-5cb8-9007-f91dee1c3208","mechanism_event_label":"Different microbes can carry out consecutive steps.","subject":{"id":"4ae3605e-f6eb-51bd-8564-8d1e37895437","slug":"e-timonensis","display_name":"Emergencia timonensis","entity_type_key":"cell_type"},"object":{"id":"b7cabc91-609a-5503-a913-15fcbd6568cc","slug":"human-microbial-gbb-tma-conversion","display_name":"Human gut microbial gamma-butyrobetaine-to-TMA conversion","entity_type_key":"cellular_process"},"evidence_count":1,"mechanism_event":{"id":"d063f31d-0412-5cb8-9007-f91dee1c3208","stable_key":"6cdb37aa-8998-5ea8-829d-4f995caf98fc:l-carnitine-microbial-coculture-event","event_type":"observed_relationship","label":"Different microbes can carry out consecutive steps.","description":"Adding E. timonensis in coculture completed the carnitine-to-TMA conversion using other microbes' gamma-butyrobetaine production.","status":"provisional","compartment":null,"participants":[{"entity":{"id":"4ae3605e-f6eb-51bd-8564-8d1e37895437","slug":"e-timonensis","display_name":"Emergencia timonensis","entity_type_key":"cell_type"},"role":"subject","stoichiometry":null,"state_label":"","sequence_order":0,"notes":""},{"entity":{"id":"b7cabc91-609a-5503-a913-15fcbd6568cc","slug":"human-microbial-gbb-tma-conversion","display_name":"Human gut microbial gamma-butyrobetaine-to-TMA conversion","entity_type_key":"cellular_process"},"role":"target","stoichiometry":null,"state_label":"","sequence_order":1,"notes":""},{"entity":{"id":"6e34c035-9371-578f-b799-fd2a14e9e40f","slug":"l-carnitine","display_name":"L-Carnitine","entity_type_key":"small_molecule"},"role":"context_participant","stoichiometry":null,"state_label":"","sequence_order":2,"notes":""},{"entity":{"id":"e83c0395-55f1-5483-9710-9b9aa9767689","slug":"gamma-butyrobetaine","display_name":"gamma-Butyrobetaine","entity_type_key":"small_molecule"},"role":"context_participant","stoichiometry":null,"state_label":"","sequence_order":3,"notes":""},{"entity":{"id":"ffdcd3fa-0e47-5c2b-96e2-00b7d1d5674e","slug":"trimethylamine","display_name":"Trimethylamine / TMA","entity_type_key":"small_molecule"},"role":"context_participant","stoichiometry":null,"state_label":"","sequence_order":4,"notes":""}]},"contexts":[{"dimension":"evidence_access","value_text":"Primary abstract","comparator":null,"unit":null,"notes":"","entity":null},{"dimension":"experimental_model","value_text":"Cultured human fecal commensals under anaerobic conditions.","comparator":null,"unit":null,"notes":"","entity":null},{"dimension":"limitations","value_text":"Community capability does not establish the abundance or activity in every person.","comparator":null,"unit":null,"notes":"","entity":null},{"dimension":"nutrient_topic","value_text":"L-Carnitine collection; 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