{"id":"6512d3a2-6fa3-527e-8fce-db565ea4088d","stable_key":"79018983-9179-5c1a-8e7a-d6f47a13582b:ki-lithium","predicate":"may_potentiate","statement":"The label warns that lithium or antithyroid drugs can add to hypothyroid and goitrogenic effects.","claim_class":"observational","status":"source_derived_draft","evidence_grade":"ungraded","direction":"context_dependent","is_public":true,"mechanism_event_id":"38a5b995-eec9-5fbf-9407-1fa25db93c6b","mechanism_event_label":"Different drugs can converge on reduced thyroid function.","subject":{"id":"d6a7fe6a-d90e-5fad-acf4-4971b24fa8d7","slug":"potassium-iodide","display_name":"Potassium iodide","entity_type_key":"chemical_species"},"object":{"id":"e8adb3a7-7b37-5f22-a6d0-2639de1785fa","slug":"goitrous-hypothyroidism","display_name":"Goitrous hypothyroidism","entity_type_key":"cellular_process"},"evidence_count":1,"mechanism_event":{"id":"38a5b995-eec9-5fbf-9407-1fa25db93c6b","stable_key":"79018983-9179-5c1a-8e7a-d6f47a13582b:ki-lithium-event","event_type":"observed_relationship","label":"Different drugs can converge on reduced thyroid function.","description":"The label warns that lithium or antithyroid drugs can add to hypothyroid and goitrogenic effects.","status":"provisional","compartment":null,"participants":[{"entity":{"id":"d6a7fe6a-d90e-5fad-acf4-4971b24fa8d7","slug":"potassium-iodide","display_name":"Potassium iodide","entity_type_key":"chemical_species"},"role":"subject","stoichiometry":null,"state_label":"","sequence_order":0,"notes":""},{"entity":{"id":"e8adb3a7-7b37-5f22-a6d0-2639de1785fa","slug":"goitrous-hypothyroidism","display_name":"Goitrous hypothyroidism","entity_type_key":"cellular_process"},"role":"target","stoichiometry":null,"state_label":"","sequence_order":1,"notes":""},{"entity":{"id":"13b4b09c-4581-58f6-9792-9a78125963e8","slug":"lithium-ion","display_name":"Lithium ion (Li+)","entity_type_key":"ion"},"role":"context_participant","stoichiometry":null,"state_label":"","sequence_order":2,"notes":""},{"entity":{"id":"a3a516d1-65de-5638-8baa-bf4571450959","slug":"methimazole","display_name":"Methimazole","entity_type_key":"small_molecule"},"role":"context_participant","stoichiometry":null,"state_label":"","sequence_order":3,"notes":""}]},"contexts":[{"dimension":"experimental_model","value_text":"2025 SSKI manufacturer label; 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