{"id":"62220c7a-9fb6-5e11-8db4-9b678e9b186c","stable_key":"d17caac5-7018-5ca8-9e96-95afeb384bc4:pectin-human-scfa-null","predicate":"did_not_significantly_change","statement":"Fecal SCFA profiles were not significantly changed.","claim_class":"observational","status":"source_derived_draft","evidence_grade":"ungraded","direction":"context_dependent","is_public":true,"mechanism_event_id":"b5a1dc62-c08e-508c-893c-cce68189fb72","mechanism_event_label":"A stool SCFA concentration reflects production, use and absorption together.","subject":{"id":"5a68dbc7-8a64-51ab-aa81-acc113c5c2dd","slug":"sugar-beet-pectin","display_name":"Sugar beet pectin","entity_type_key":"chemical_species"},"object":{"id":"9d7d8d6b-6615-51f0-8194-a4b5c28da45c","slug":"fecal-scfa-concentrations","display_name":"Human fecal short-chain fatty acid concentrations","entity_type_key":"cellular_process"},"evidence_count":1,"mechanism_event":{"id":"b5a1dc62-c08e-508c-893c-cce68189fb72","stable_key":"d17caac5-7018-5ca8-9e96-95afeb384bc4:pectin-human-scfa-null-event","event_type":"observed_intervention","label":"A stool SCFA concentration reflects production, use and absorption together.","description":"Fecal SCFA profiles were not significantly changed.","status":"provisional","compartment":null,"participants":[{"entity":{"id":"5a68dbc7-8a64-51ab-aa81-acc113c5c2dd","slug":"sugar-beet-pectin","display_name":"Sugar beet pectin","entity_type_key":"chemical_species"},"role":"subject","stoichiometry":null,"state_label":"","sequence_order":0,"notes":""},{"entity":{"id":"9d7d8d6b-6615-51f0-8194-a4b5c28da45c","slug":"fecal-scfa-concentrations","display_name":"Human fecal short-chain fatty acid concentrations","entity_type_key":"cellular_process"},"role":"target","stoichiometry":null,"state_label":"","sequence_order":1,"notes":""}]},"contexts":[{"dimension":"evidence_span","value_text":"{\"source_cache\": \"artifacts/pectin-research/31547291.abstract.txt\", \"locator\": \"Primary indexed abstract; zero-based, end-exclusive Unicode character offsets\", \"file_sha256\": \"cd2a4b1f6d299d573d8ea5077447bc45c8d8c6da58fa25c7835f01c5488d9db4\", \"start_char\": 0, \"end_char\": 1451, \"text_sha256\": \"cd2a4b1f6d299d573d8ea5077447bc45c8d8c6da58fa25c7835f01c5488d9db4\"}","comparator":null,"unit":null,"notes":"","entity":null},{"dimension":"experimental_model","value_text":"Randomized placebo-controlled feeding; young and older healthy adults","comparator":null,"unit":null,"notes":"","entity":null},{"dimension":"exposure","value_text":"15 g/day sugar beet pectin versus maltodextrin for four weeks","comparator":null,"unit":null,"notes":"","entity":null},{"dimension":"limitations","value_text":"Related analysis of the same cohort as PMID31324040, not an independent replication. Fecal concentration is not production flux.","comparator":null,"unit":null,"notes":"","entity":null},{"dimension":"nutrient_topic","value_text":"Pectin research collection; topical membership is not evidence of a direct dietary effect.","comparator":null,"unit":null,"notes":"","entity":{"slug":"pectin","display_name":"Pectin, structurally heterogeneous plant polysaccharides","entity_type_key":"chemical_species"}},{"dimension":"organism","value_text":"Homo sapiens","comparator":null,"unit":null,"notes":"","entity":null},{"dimension":"plain_language","value_text":"A stool SCFA concentration reflects production, use and absorption together.","comparator":null,"unit":null,"notes":"","entity":null},{"dimension":"primary_references","value_text":"[pectin-p31547291] Sugar Beet Pectin Supplementation Did Not Alter Profiles of Fecal Microbiota and Exhaled Breath in Healthy Young Adults and Healthy Elderly. (2019). https://pubmed.ncbi.nlm.nih.gov/31547291/ DOI: 10.3390/nu11092193","comparator":null,"unit":null,"notes":"","entity":null},{"dimension":"tissue_or_cell_type","value_text":"Feces and microbial profiling","comparator":null,"unit":null,"notes":"","entity":null}],"evidence":[{"id":"89ee86a4-df18-5a8a-a2bc-abf96c0a16e1","evidence_kind":"source_excerpt","locator":"Lines 1010-1021","start_line":1010,"end_line":1021,"excerpt":"### pectin-human-scfa-null\nFecal SCFA profiles were not significantly changed.\nCondition category: normal\nnutrient_topic: Pectin research collection; topical membership is not evidence of a direct dietary effect.\nplain_language: A stool SCFA concentration reflects production, use and absorption together.\norganism: Homo sapiens\ntissue_or_cell_type: Feces and microbial profiling\nexperimental_model: Randomized placebo-controlled feeding; young and older healthy adults\nlimitations: Related analysis of the same cohort as PMID31324040, not an independent replication. Fecal concentration is not production flux.\nexposure: 15 g/day sugar beet pectin versus maltodextrin for four weeks\nevidence_span: {\"source_cache\": \"artifacts/pectin-research/31547291.abstract.txt\", \"locator\": \"Primary indexed abstract; zero-based, end-exclusive Unicode character offsets\", \"file_sha256\": \"cd2a4b1f6d299d573d8ea5077447bc45c8d8c6da58fa25c7835f01c5488d9db4\", \"start_char\": 0, \"end_char\": 1451, \"text_sha256\": \"cd2a4b1f6d299d573d8ea5077447bc45c8d8c6da58fa25c7835f01c5488d9db4\"}\n[pectin-p31547291] Sugar Beet Pectin Supplementation Did Not Alter Profiles of Fecal Microbiota and Exhaled Breath in Healthy Young Adults and Healthy Elderly. (2019). https://pubmed.ncbi.nlm.nih.gov/31547291/ DOI: 10.3390/nu11092193","model_system":"Randomized placebo-controlled feeding; young and older healthy adults","directness":"author_interpretation","verification_status":"source_derived_draft","notes":"Exact curation-document quotation, not publisher quotation. 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