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It establishes a receptor, which is what displaced the membrane-disruption explanation of cannabinoid action.\nexposure: Cannabinoid binding and adenylate cyclase inhibition in the transfected cells\nevidence_span: {\"source_cache\": \"artifacts/thc-research/2165569.abstract.txt\", \"locator\": \"Indexed abstract; zero-based, end-exclusive Unicode character offsets\", \"file_sha256\": \"8d92b7104006ccc194ab498aa8f559606353e6ccc4b5aa7af0a9502c9bfc37db\", \"start_char\": 0, \"end_char\": 1256, \"text_sha256\": \"8d92b7104006ccc194ab498aa8f559606353e6ccc4b5aa7af0a9502c9bfc37db\"}\n[thc-p2165569] Structure of a cannabinoid receptor and functional expression of the cloned cDNA. (1990). https://pubmed.ncbi.nlm.nih.gov/2165569/ DOI: 10.1038/346561a0","model_system":"Cloning and heterologous expression of a complementary DNA from rat brain","directness":"author_interpretation","verification_status":"source_derived_draft","notes":"Exact curation-document quotation, not publisher quotation. 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