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It does not establish that dietary phytate reaches this intracellular site or overrides InsP8 selectivity in other assays.","comparator":null,"unit":null,"notes":"","entity":null},{"dimension":"nutrient_topic","value_text":"Inositol research collection; topical membership is not evidence of a direct dietary effect.","comparator":null,"unit":null,"notes":"","entity":{"slug":"inositol","display_name":"Inositol (stereoisomer family)","entity_type_key":"chemical_species"}},{"dimension":"organism","value_text":"Human proteins","comparator":null,"unit":null,"notes":"","entity":null},{"dimension":"plain_language","value_text":"An intracellular inositol phosphate helped stabilize an open exporter complex.","comparator":null,"unit":null,"notes":"","entity":null},{"dimension":"primary_references","value_text":"[ino-p40128258] Synergistic activation of the human phosphate exporter XPR1 by KIDINS220 and inositol pyrophosphate. 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It does not establish that dietary phytate reaches this intracellular site or overrides InsP8 selectivity in other assays.\nexposure: InsP6 and phosphate binding\nevidence_span: {\"source_cache\": \"artifacts/inositol-research/40128258.abstract.txt\", \"locator\": \"Exact primary indexed abstract; zero-based, end-exclusive Unicode character offsets\", \"file_sha256\": \"4765253840f684d5dafa834980e3fea9edc5d7419379b4a27ccf1090f081ce00\", \"start_char\": 0, \"end_char\": 1071, \"text_sha256\": \"4765253840f684d5dafa834980e3fea9edc5d7419379b4a27ccf1090f081ce00\"}\n[ino-p40128258] Synergistic activation of the human phosphate exporter XPR1 by KIDINS220 and inositol pyrophosphate. (2025). https://pubmed.ncbi.nlm.nih.gov/40128258/ DOI: 10.1038/s41467-025-58200-y","model_system":"Cryo-EM and functional mutagenesis","directness":"author_interpretation","verification_status":"source_derived_draft","notes":"Exact curation-document quotation, not publisher quotation. 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