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(2011). https://pubmed.ncbi.nlm.nih.gov/21430075/ DOI: 10.1158/1940-6207.capr-10-0288","comparator":null,"unit":null,"notes":"","entity":null},{"dimension":"tissue_or_cell_type","value_text":"Plasma and prostate biopsy","comparator":null,"unit":null,"notes":"","entity":null}],"evidence":[{"id":"cd500c07-8d3b-50e7-a24f-f26772ca99de","evidence_kind":"source_excerpt","locator":"Lines 1092-1103","start_line":1092,"end_line":1103,"excerpt":"### lycopene-prostate-dna-oxidation-null\nNo significant reduction in prostate 8-oxo-deoxyguanosine followed lycopene treatment.\nCondition category: normal\nnutrient_topic: Lycopene research collection; topical membership is not evidence of a direct dietary effect.\nplain_language: A DNA-oxidation marker did not improve despite increased exposure.\norganism: Human, 105 African American male veterans\ntissue_or_cell_type: Plasma and prostate biopsy\nexperimental_model: Double-blind placebo-controlled prebiopsy trial\nlimitations: Short exposure; tissue and oxidation biomarkers do not establish cancer prevention or clinical benefit.\nexposure: 30 mg/day tomato-oleoresin lycopene for 21 days\nevidence_span: {\"source_cache\": \"artifacts/lycopene-research/21430075.abstract.txt\", \"locator\": \"Primary indexed abstract; zero-based, end-exclusive Unicode character offsets\", \"file_sha256\": \"c1351b40c0701ce0b8e35bc9346b63650fbd2ee3a9263091aa6b304b9860a5e3\", \"start_char\": 0, \"end_char\": 1314, \"text_sha256\": \"c1351b40c0701ce0b8e35bc9346b63650fbd2ee3a9263091aa6b304b9860a5e3\"}\n[lycopene-p21430075] Antioxidant effects of lycopene in African American men with prostate cancer or benign prostate hyperplasia: a randomized, controlled trial. 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