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(2017). https://pubmed.ncbi.nlm.nih.gov/28813664/ DOI: 10.1016/j.celrep.2017.07.057","comparator":null,"unit":null,"notes":"","entity":null},{"dimension":"tissue_or_cell_type","value_text":"Gut microbiota and skin","comparator":null,"unit":null,"notes":"","entity":null},{"dimension":"trigger_kind","value_text":"nutrient_deficiency","comparator":null,"unit":null,"notes":"Imported condition classification; unverified.","entity":null}],"evidence":[{"id":"c2fd947b-ae59-5520-88ac-1b2d5029c6f6","evidence_kind":"source_excerpt","locator":"Lines 1144-1155","start_line":1144,"end_line":1155,"excerpt":"### b7-microbiome-alopecia\nBiotin restored hair in SPF mice with established alopecia after combined dietary deprivation and vancomycin-associated dysbiosis.\nCondition category: nutrient_deficiency\nnutrient_topic: Biotin research collection; topical membership is not evidence of a direct dietary effect.\nplain_language: Correction helped in this experimentally induced mouse deficiency state.\norganism: Mus musculus\ntissue_or_cell_type: Gut microbiota and skin\nexperimental_model: SPF and gnotobiotic mouse experiments with diet, vancomycin and Lactobacillus murinus\nlimitations: Mouse experimental ecology does not diagnose the cause of human alopecia or justify targeting a bacterial species in people.\nexposure: Biotin-deprived diet plus microbiota manipulation\nevidence_span: {\"source_cache\": \"artifacts/biotin-research/28813664.abstract.txt\", \"locator\": \"Exact primary indexed abstract; zero-based, end-exclusive Unicode character offsets\", \"file_sha256\": \"a672505b5121e4c99b21436c378624a7a8eca2576090dba1f59b4a989182e7a9\", \"start_char\": 0, \"end_char\": 1065, \"text_sha256\": \"a672505b5121e4c99b21436c378624a7a8eca2576090dba1f59b4a989182e7a9\"}\n[b7-p28813664] Intestinal Dysbiosis and Biotin Deprivation Induce Alopecia through Overgrowth of Lactobacillus murinus in Mice. 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