{"id":"51751bb5-857d-5b8c-b3c1-3ddc5c5711c0","stable_key":"41a89233-da9a-5b7b-9c18-e19bbadcfe2d:methionine-mars-charging","predicate":"charges","statement":"Human MARS1 catalyzes methionylation of cognate tRNA; the study compared this activity with stress-induced charging of non-cognate tRNAs.","claim_class":"mechanistic","status":"source_derived_draft","evidence_grade":"ungraded","direction":"context_dependent","is_public":true,"mechanism_event_id":"cc4d8be7-ee04-5fb4-b87b-af7ee1a82bdf","mechanism_event_label":"A dedicated enzyme attaches methionine to the translation machinery.","subject":{"id":"d66988d4-32f5-5d3f-9d5e-e3035886d544","slug":"mars1","display_name":"Human cytosolic methionyl-tRNA synthetase / MARS1","entity_type_key":"protein"},"object":{"id":"86abd69f-5eed-5d32-9859-1e6a80b7d059","slug":"human-cytosolic-methionyl-trna","display_name":"Human cytosolic methionyl-tRNA","entity_type_key":"rna"},"evidence_count":1,"mechanism_event":{"id":"cc4d8be7-ee04-5fb4-b87b-af7ee1a82bdf","stable_key":"41a89233-da9a-5b7b-9c18-e19bbadcfe2d:methionine-mars-charging-event","event_type":"observed_relationship","label":"A dedicated enzyme attaches methionine to the translation machinery.","description":"Human MARS1 catalyzes methionylation of cognate tRNA; 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