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(2025). https://pubmed.ncbi.nlm.nih.gov/39942566/ DOI: 10.3390/molecules30030461","comparator":null,"unit":null,"notes":"","entity":null},{"dimension":"tissue_or_cell_type","value_text":"Plasma","comparator":null,"unit":null,"notes":"","entity":null}],"evidence":[{"id":"ec120460-ec05-5824-8c6a-f3914e4d3382","evidence_kind":"source_excerpt","locator":"Lines 262-273","start_line":262,"end_line":273,"excerpt":"### mangiferin-salt-exposure\nMLES produced 2.44-fold higher AUC over 24 hours than MLE60 in the crossover comparison.\nCondition category: normal\nnutrient_topic: Mangiferin research collection; topical membership is not evidence of a direct dietary effect.\nplain_language: The soluble salt preparation changed circulating exposure.\norganism: 12 adults, six women\ntissue_or_cell_type: Plasma\nexperimental_model: Human crossover pharmacokinetic comparison\nlimitations: Relative exposure comparison of formulations, not absolute bioavailability, pure-compound equivalence or demonstrated clinical benefit.\nexposure: Two standardized 60% mango-leaf extracts; seven-day washout\nevidence_span: {\"source_cache\": \"artifacts/mangiferin-research/39942566.abstract.txt\", \"locator\": \"Primary indexed abstract; zero-based, end-exclusive Unicode character offsets\", \"file_sha256\": \"7f3b135e29a0a2b6268f49880822ee862a25c62b401ef8046a5feb1667b06330\", \"start_char\": 0, \"end_char\": 1283, \"text_sha256\": \"7f3b135e29a0a2b6268f49880822ee862a25c62b401ef8046a5feb1667b06330\"}\n[mangiferin-p39942566] Human Pharmacokinetic Profiling and Comparative Analysis of Mangiferin and Its Monosodium Derivative from Mangifera indica Extracts Using UHPLC-MS/MS with 1H NMR and MALDI-TOF Confirmation. 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