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Abstract wording for the 80-30000-fold IC50 comparison is ambiguous and is not used as a potency estimate.","comparator":null,"unit":null,"notes":"","entity":null},{"dimension":"nutrient_topic","value_text":"L-Theanine research collection; topical membership is not evidence of a direct dietary effect.","comparator":null,"unit":null,"notes":"","entity":{"slug":"theanine","display_name":"L-Theanine","entity_type_key":"small_molecule"}},{"dimension":"organism","value_text":"Rat cortical preparations","comparator":null,"unit":null,"notes":"","entity":null},{"dimension":"plain_language","value_text":"A binding assay identifies a possible receptor interaction while leaving functional and clinical effects unresolved.","comparator":null,"unit":null,"notes":"","entity":null},{"dimension":"primary_references","value_text":"[theanine-p12596867] Inhibition by theanine of binding of [3H]AMPA, [3H]kainate, and [3H]MDL 105,519 to glutamate receptors. 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Abstract wording for the 80-30000-fold IC50 comparison is ambiguous and is not used as a potency estimate.\nexposure: Theanine competition with radiolabeled ligands\nevidence_span: {\"source_cache\": \"artifacts/theanine-research/12596867.abstract.txt\", \"locator\": \"Primary indexed abstract; zero-based, end-exclusive Unicode character offsets\", \"file_sha256\": \"eaa387f7967a1ff8e68eceb71fd3294881967066c5dc080fd27bacf8a01ce33d\", \"start_char\": 0, \"end_char\": 643, \"text_sha256\": \"eaa387f7967a1ff8e68eceb71fd3294881967066c5dc080fd27bacf8a01ce33d\"}\n[theanine-p12596867] Inhibition by theanine of binding of [3H]AMPA, [3H]kainate, and [3H]MDL 105,519 to glutamate receptors. (2002). https://pubmed.ncbi.nlm.nih.gov/12596867/ DOI: 10.1271/bbb.66.2683","model_system":"Radioligand receptor-binding competition","directness":"author_interpretation","verification_status":"source_derived_draft","notes":"Exact curation-document quotation, not publisher quotation. 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