{"id":"4b19e010-98b1-5eee-8a1a-e1289bc92fbb","stable_key":"9a47f338-d127-5e4d-abf6-e99056833a69:d-aspartate-srr-racemization","predicate":"catalyzes","statement":"Purified mammalian serine racemase catalyzed aspartate racemization in the reported two-base reaction mechanism.","claim_class":"mechanistic","status":"source_derived_draft","evidence_grade":"ungraded","direction":"context_dependent","is_public":true,"mechanism_event_id":"c8a3b7a4-dd64-57fc-b192-d259bdfd9270","mechanism_event_label":"An enzyme best known for serine can also change aspartate chirality.","subject":{"id":"08aec6b5-36e7-52d8-87bd-c0bf7adc43fc","slug":"mammalian-srr-assay","display_name":"Mammalian serine-racemase assay, species unresolved in accessed abstract","entity_type_key":"protein"},"object":{"id":"b3404670-6db1-517f-b9a0-27ecfaac558b","slug":"d-aspartate","display_name":"D-Aspartate","entity_type_key":"small_molecule"},"evidence_count":1,"mechanism_event":{"id":"c8a3b7a4-dd64-57fc-b192-d259bdfd9270","stable_key":"9a47f338-d127-5e4d-abf6-e99056833a69:d-aspartate-srr-racemization-event","event_type":"observed_relationship","label":"An enzyme best known for serine can also change aspartate chirality.","description":"Purified mammalian serine racemase catalyzed aspartate racemization in the reported two-base reaction mechanism.","status":"provisional","compartment":null,"participants":[{"entity":{"id":"08aec6b5-36e7-52d8-87bd-c0bf7adc43fc","slug":"mammalian-srr-assay","display_name":"Mammalian serine-racemase assay, species unresolved in accessed abstract","entity_type_key":"protein"},"role":"subject","stoichiometry":null,"state_label":"","sequence_order":0,"notes":""},{"entity":{"id":"b3404670-6db1-517f-b9a0-27ecfaac558b","slug":"d-aspartate","display_name":"D-Aspartate","entity_type_key":"small_molecule"},"role":"target","stoichiometry":null,"state_label":"","sequence_order":1,"notes":""},{"entity":{"id":"0a0923d3-72b7-5d6a-bf3a-5a7a3071a09b","slug":"l-aspartate","display_name":"L-Aspartate","entity_type_key":"small_molecule"},"role":"context_participant","stoichiometry":null,"state_label":"","sequence_order":2,"notes":""}]},"contexts":[{"dimension":"evidence_access","value_text":"Primary abstract","comparator":null,"unit":null,"notes":"","entity":null},{"dimension":"experimental_model","value_text":"Recombinant mammalian enzyme; protein species not resolved in the accessed abstract.","comparator":null,"unit":null,"notes":"","entity":null},{"dimension":"limitations","value_text":"Do not substitute a specific human enzyme identity or infer rates in intact human tissues.","comparator":null,"unit":null,"notes":"","entity":null},{"dimension":"nutrient_topic","value_text":"D-Aspartate collection; species, compartment, exposure, co-substrates and manipulation remain explicit.","comparator":null,"unit":null,"notes":"","entity":{"slug":"d-aspartate","display_name":"D-Aspartate","entity_type_key":"small_molecule"}},{"dimension":"plain_language","value_text":"An enzyme best known for serine can also change aspartate chirality.","comparator":null,"unit":null,"notes":"","entity":null},{"dimension":"primary_references","value_text":"Serine racemase is involved in d-aspartate biosynthesis. · 2016 · https://pubmed.ncbi.nlm.nih.gov/27387750/ · DOI 10.1093/jb/mvw043","comparator":null,"unit":null,"notes":"","entity":null}],"evidence":[{"id":"8be21ba5-8ecb-5011-80ba-2bb754d5fa5f","evidence_kind":"source_excerpt","locator":"Lines 16-22","start_line":16,"end_line":22,"excerpt":"## d-aspartate-srr-racemization\nAn enzyme best known for serine can also change aspartate chirality.\nPurified mammalian serine racemase catalyzed aspartate racemization in the reported two-base reaction mechanism.\nModel: Recombinant mammalian enzyme; protein species not resolved in the accessed abstract.\nLimitations: Do not substitute a specific human enzyme identity or infer rates in intact human tissues.\nEvidence access: Primary abstract\nSerine racemase is involved in d-aspartate biosynthesis. · 2016 · https://pubmed.ncbi.nlm.nih.gov/27387750/ · DOI 10.1093/jb/mvw043","model_system":"Recombinant mammalian enzyme; protein species not resolved in the accessed abstract.","directness":"reported_statement","verification_status":"source_derived_draft","notes":"Original curation paraphrase; evidence access and experimental limitations specified.","relationship":"supports","weight":1.0,"link_notes":"","source":{"id":"3751103e-e256-5615-b24f-39cc76ccfb47","stable_key":"import-9a47f338-d127-5e4d-abf6-e99056833a69","title":"D-Aspartate: synthesis, clearance, neural and endocrine mechanisms (2026-09-19)","document_type":"imported_text","citation_label":"AI-assisted research curation; primary references, access levels and experimental limitations individually identified. 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