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It establishes how much copper the enzyme needs, not how much copper a person needs.","comparator":null,"unit":null,"notes":"","entity":null},{"dimension":"nutrient_topic","value_text":"Cold water immersion research collection; topical membership is not evidence of a direct clinical effect, and a therapeutic exposure is not a dietary intake.","comparator":null,"unit":null,"notes":"","entity":{"slug":"cold-water-immersion","display_name":"Cold water immersion","entity_type_key":"drug"}},{"dimension":"organism","value_text":"Bovine enzyme","comparator":null,"unit":null,"notes":"","entity":null},{"dimension":"plain_language","value_text":"The enzyme that turns dopamine into noradrenaline needs exactly eight copper atoms to work fully.","comparator":null,"unit":null,"notes":"","entity":null},{"dimension":"primary_references","value_text":"[cold-p6323422] Kinetic and spectroscopic studies of the interaction of copper with dopamine beta-hydroxylase. 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It establishes how much copper the enzyme needs, not how much copper a person needs.\nexposure: Titration with copper and measurement of catalytic rate\nevidence_span: {\"source_cache\": \"artifacts/cold-research/6323422.abstract.txt\", \"locator\": \"Indexed abstract; zero-based, end-exclusive Unicode character offsets\", \"file_sha256\": \"dac85ce0ad7c7d5994b97d55b129050a0e7ca8bf96943578d272054db6a07a62\", \"start_char\": 0, \"end_char\": 1346, \"text_sha256\": \"dac85ce0ad7c7d5994b97d55b129050a0e7ca8bf96943578d272054db6a07a62\"}\n[cold-p6323422] Kinetic and spectroscopic studies of the interaction of copper with dopamine beta-hydroxylase. 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