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(2006). https://pubmed.ncbi.nlm.nih.gov/16672231/ DOI: 10.1074/jbc.m512095200","comparator":null,"unit":null,"notes":"","entity":null},{"dimension":"tissue_or_cell_type","value_text":"BCO2 enzyme; hepatic fractions and lung","comparator":null,"unit":null,"notes":"","entity":null}],"evidence":[{"id":"fa624396-0a9a-58f2-a4cf-21c791868ab0","evidence_kind":"source_excerpt","locator":"Lines 351-362","start_line":351,"end_line":362,"excerpt":"### lycopene-apo-nadh\nNADH supported conversion of apo-10-prime-lycopenal to apo-10-prime-lycopenol in ferret hepatic fractions.\nCondition category: normal\nnutrient_topic: Lycopene research collection; topical membership is not evidence of a direct dietary effect.\nplain_language: The reduced form of the cofactor instead supported an alcohol product.\norganism: Ferret\ntissue_or_cell_type: BCO2 enzyme; hepatic fractions and lung\nexperimental_model: Recombinant ferret enzyme and tissue-fraction metabolism\nlimitations: Ferret experiments do not quantify human cleavage flux or predict supplement response.\nexposure: 5-cis, 13-cis and all-trans lycopene; iron; NAD+ or NADH\nevidence_span: {\"source_cache\": \"artifacts/lycopene-research/16672231.abstract.txt\", \"locator\": \"Primary indexed abstract; zero-based, end-exclusive Unicode character offsets\", \"file_sha256\": \"135695c9d3106469d8d64ec0806ba5bf048f0f1df6f3e3cd53e838e50b960445\", \"start_char\": 0, \"end_char\": 1967, \"text_sha256\": \"135695c9d3106469d8d64ec0806ba5bf048f0f1df6f3e3cd53e838e50b960445\"}\n[lycopene-p16672231] The biochemical characterization of ferret carotene-9',10'-monooxygenase catalyzing cleavage of carotenoids in vitro and in vivo. 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