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(1996). https://pubmed.ncbi.nlm.nih.gov/8670053/ DOI: 10.1042/bj3140433","comparator":null,"unit":null,"notes":"","entity":null},{"dimension":"tissue_or_cell_type","value_text":"MRP-overexpressing membranes","comparator":null,"unit":null,"notes":"","entity":null}],"evidence":[{"id":"f8677dc5-d5b1-5bde-87b4-ed7a6fe19105","evidence_kind":"source_excerpt","locator":"Lines 723-734","start_line":723,"end_line":734,"excerpt":"### glutathione-mrp-gssg\nMRP1 mediated ATP-dependent GSSG transport; the HeLa-vesicle Km was 93 ± 26 micromolar.\nCondition category: normal\nnutrient_topic: Glutathione research collection; topical membership is not evidence of a direct dietary effect.\nplain_language: Oxidized glutathione can be exported instead of recycled locally.\norganism: Human HL60 and HeLa systems\ntissue_or_cell_type: MRP-overexpressing membranes\nexperimental_model: Membrane-vesicle transport assays\nlimitations: Vesicle uptake reflects cellular export; the GSH null result applies specifically to the tested 100 micromolar condition.\nexposure: ATP-dependent GSSG uptake into vesicles\nevidence_span: {\"source_cache\": \"artifacts/glutathione-research/8670053.abstract.txt\", \"locator\": \"Primary indexed abstract; zero-based, end-exclusive Unicode character offsets\", \"file_sha256\": \"9178e466ea8bd18f0957cc65594934ec1681ad7483e6ac64d79c4b8d8ca2afc3\", \"start_char\": 0, \"end_char\": 1433, \"text_sha256\": \"9178e466ea8bd18f0957cc65594934ec1681ad7483e6ac64d79c4b8d8ca2afc3\"}\n[glutathione-p8670053] ATP-dependent glutathione disulphide transport mediated by the MRP gene-encoded conjugate export pump. 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