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It establishes how priming works and what it requires, not that the same sequence occurs in a treated patient.\nexposure: Soluble CR3-specific polysaccharides including beta-glucan, with antibody blockade before or after the sugar\nevidence_span: {\"source_cache\": \"artifacts/glucan-research/8690804.abstract.txt\", \"locator\": \"Indexed abstract; zero-based, end-exclusive Unicode character offsets\", \"file_sha256\": \"e6e6ce1cbb7d4a4d3170e4b86ac33d4b3220d59645c53d757fe3a2681397287e\", \"start_char\": 0, \"end_char\": 1478, \"text_sha256\": \"e6e6ce1cbb7d4a4d3170e4b86ac33d4b3220d59645c53d757fe3a2681397287e\"}\n[bg-p8690804] Soluble beta-glucan polysaccharide binding to the lectin site of neutrophil or natural killer cell complement receptor type 3 (CD11b/CD18) generates a primed state of the receptor capable of mediating cytotoxicity of iC3b-opsonized target cells. 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