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Potencies come from recombinant systems, not from tissue, and the authors state plainly that the cognate physiological ligands are not clear.\nexposure: Short chain carboxylic acid anions applied to recombinant GPR41 and GPR43\nevidence_span: {\"source_cache\": \"artifacts/acetate-research/12496283.abstract.txt\", \"locator\": \"Indexed abstract; zero-based, end-exclusive Unicode character offsets\", \"file_sha256\": \"83f7777cab02a7c69f063d21e26f895884724f46ad539ebc767d9e6f371bf64f\", \"start_char\": 0, \"end_char\": 1291, \"text_sha256\": \"83f7777cab02a7c69f063d21e26f895884724f46ad539ebc767d9e6f371bf64f\"}\n[acetate-p12496283] The Orphan G protein-coupled receptors GPR41 and GPR43 are activated by propionate and other short chain carboxylic acids. 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