{"id":"2e818704-e345-5af4-a0e5-2bbd0768b08f","stable_key":"16c35a72-8162-5bb1-ae01-45331b8b42d0:moringa-moringin-trpa1","predicate":"activates","statement":"Purified moringin acted as a potent agonist of human TRPA1 in vitro.","claim_class":"mechanistic","status":"source_derived_draft","evidence_grade":"ungraded","direction":"positive","is_public":true,"mechanism_event_id":"deaa1376-e000-566f-8419-012c27800645","mechanism_event_label":"Purified moringin acted as a potent agonist of human TRPA1 in vitro.","subject":{"id":"18d01b02-1f9f-5dfd-8df2-a27c1899fa9c","slug":"moringin","display_name":"Moringin / MIC-1","entity_type_key":"small_molecule"},"object":{"id":"44366bfb-222d-5da6-911a-e853c3d7cdb7","slug":"human-trpa1","display_name":"Human TRPA1 ion channel","entity_type_key":"protein"},"evidence_count":1,"mechanism_event":{"id":"deaa1376-e000-566f-8419-012c27800645","stable_key":"16c35a72-8162-5bb1-ae01-45331b8b42d0:moringa-moringin-trpa1-event","event_type":"observed_relationship","label":"Purified moringin acted as a potent agonist of human TRPA1 in vitro.","description":"Purified moringin acted as a potent agonist of human TRPA1 in vitro.","status":"provisional","compartment":null,"participants":[{"entity":{"id":"18d01b02-1f9f-5dfd-8df2-a27c1899fa9c","slug":"moringin","display_name":"Moringin / MIC-1","entity_type_key":"small_molecule"},"role":"subject","stoichiometry":null,"state_label":"","sequence_order":0,"notes":""},{"entity":{"id":"44366bfb-222d-5da6-911a-e853c3d7cdb7","slug":"human-trpa1","display_name":"Human TRPA1 ion channel","entity_type_key":"protein"},"role":"target","stoichiometry":null,"state_label":"","sequence_order":1,"notes":""}]},"contexts":[{"dimension":"dose","value_text":"Purified moringin concentration series","comparator":null,"unit":null,"notes":"","entity":null},{"dimension":"duration","value_text":"Acute","comparator":null,"unit":null,"notes":"","entity":null},{"dimension":"evidence_access","value_text":"Primary PubMed abstract and indexed metadata reviewed. 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