{"id":"2a81af27-7dc6-5bbe-9bd1-9536479003e6","stable_key":"649e861b-265a-5912-bc36-3a73e53ef892:l-serine-sfxn1-loss","predicate":"supports","statement":"SFXN1-null human cells had impaired glycine and purine synthesis; loss of both SFXN1 and SFXN3 caused stronger defects, including dependence on exogenous glycine.","claim_class":"mechanistic","status":"source_derived_draft","evidence_grade":"ungraded","direction":"context_dependent","is_public":true,"mechanism_event_id":"44f875c0-0fce-5358-862b-c74b27913def","mechanism_event_label":"Transport capacity can limit another amino acid and nucleotide production.","subject":{"id":"8d8fb144-4bb5-5b97-8a22-207c2e9c5206","slug":"sfxn1","display_name":"Human sideroflexin 1 / SFXN1","entity_type_key":"protein"},"object":{"id":"4367e5c3-081e-547d-abed-1dc9f3895e96","slug":"human-sfxn1-glycine-purine-synthesis","display_name":"Glycine and purine synthesis in human SFXN1-deficient cells","entity_type_key":"cellular_process"},"evidence_count":1,"mechanism_event":{"id":"44f875c0-0fce-5358-862b-c74b27913def","stable_key":"649e861b-265a-5912-bc36-3a73e53ef892:l-serine-sfxn1-loss-event","event_type":"observed_relationship","label":"Transport capacity can limit another amino acid and nucleotide production.","description":"SFXN1-null human cells had impaired glycine and purine synthesis; 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