{"id":"253e6e28-62be-5cc1-af53-45503781188e","stable_key":"c932089b-ebc9-5f39-b2e5-84af74f9f6d0:sucrose-absorption","predicate":"no_detected_malabsorption","statement":"None of ten healthy volunteers showed breath-hydrogen malabsorption after the tested 50, 75 or 100 g sucrose loads.","claim_class":"observational","status":"source_derived_draft","evidence_grade":"ungraded","direction":"neutral","is_public":true,"mechanism_event_id":"c560c0e7-4a4f-540e-a0af-6c23889e1019","mechanism_event_label":"None of ten healthy volunteers showed breath-hydrogen malabsorption after the tested 50, 75 or 100 g sucrose loads.","subject":{"id":"82558bd0-1a84-574a-a04c-10609c9c5dba","slug":"sucrose","display_name":"Sucrose","entity_type_key":"small_molecule"},"object":{"id":"414cde7c-8aaa-513e-a6cc-e9c30b1ba8e8","slug":"human-sucrose-breath-test-malabsorption","display_name":"Human sucrose malabsorption assessed by breath hydrogen","entity_type_key":"cellular_process"},"evidence_count":1,"mechanism_event":{"id":"c560c0e7-4a4f-540e-a0af-6c23889e1019","stable_key":"c932089b-ebc9-5f39-b2e5-84af74f9f6d0:sucrose-absorption-event","event_type":"observed_relationship","label":"None of ten healthy volunteers showed breath-hydrogen malabsorption after the tested 50, 75 or 100 g sucrose loads.","description":"None of ten healthy volunteers showed breath-hydrogen malabsorption after the tested 50, 75 or 100 g sucrose loads.","status":"provisional","compartment":null,"participants":[{"entity":{"id":"82558bd0-1a84-574a-a04c-10609c9c5dba","slug":"sucrose","display_name":"Sucrose","entity_type_key":"small_molecule"},"role":"subject","stoichiometry":null,"state_label":"","sequence_order":0,"notes":""},{"entity":{"id":"414cde7c-8aaa-513e-a6cc-e9c30b1ba8e8","slug":"human-sucrose-breath-test-malabsorption","display_name":"Human sucrose malabsorption assessed by breath hydrogen","entity_type_key":"cellular_process"},"role":"target","stoichiometry":null,"state_label":"","sequence_order":1,"notes":""}]},"contexts":[{"dimension":"dose","value_text":"Sucrose 50, 75 or 100 g; comparison with fructose alone","comparator":null,"unit":null,"notes":"","entity":null},{"dimension":"duration","value_text":"Breath sampling over 3-4 hours","comparator":null,"unit":null,"notes":"","entity":null},{"dimension":"evidence_access","value_text":"Primary abstract/metadata; unrecovered methods explicitly retained.","comparator":null,"unit":null,"notes":"","entity":null},{"dimension":"evidence_scope","value_text":"literature_reviewed; source-specific curation","comparator":null,"unit":null,"notes":"","entity":null},{"dimension":"experimental_model","value_text":"Ten healthy adult volunteers","comparator":null,"unit":null,"notes":"","entity":null},{"dimension":"exposure_scope","value_text":"Human sucrose absorption","comparator":null,"unit":null,"notes":"","entity":null},{"dimension":"limitations","value_text":"No detected breath-hydrogen malabsorption in a small healthy cohort is not proof that every person tolerates every dose; CSID is a distinct condition.","comparator":null,"unit":null,"notes":"","entity":null},{"dimension":"nutrient_topic","value_text":"Sucrose chapter; direct sucrose observations are distinguished from shared component metabolism.","comparator":null,"unit":null,"notes":"","entity":{"slug":"sucrose","display_name":"Sucrose","entity_type_key":"small_molecule"}},{"dimension":"organism","value_text":"Ten healthy adult volunteers","comparator":null,"unit":null,"notes":"","entity":null},{"dimension":"plain_language","value_text":"None of ten healthy volunteers showed breath-hydrogen malabsorption after the tested 50, 75 or 100 g sucrose loads.","comparator":null,"unit":null,"notes":"","entity":null},{"dimension":"primary_references","value_text":"Absorption capacity of fructose in healthy adults. Comparison with sucrose and its constituent monosaccharides. (1986). https://pubmed.ncbi.nlm.nih.gov/3781328/ DOI: 10.1136/gut.27.10.1161","comparator":null,"unit":null,"notes":"","entity":null},{"dimension":"route","value_text":"Oral sugar solutions","comparator":null,"unit":null,"notes":"","entity":null},{"dimension":"tissue","value_text":"Hydrogen breath tests","comparator":null,"unit":null,"notes":"","entity":null}],"evidence":[{"id":"75ce6972-2a6f-56ad-9563-ba0326c82238","evidence_kind":"source_excerpt","locator":"Lines 391-401","start_line":391,"end_line":401,"excerpt":"## sucrose-absorption\nNone of ten healthy volunteers showed breath-hydrogen malabsorption after the tested 50, 75 or 100 g sucrose loads.\nModel/species: Ten healthy adult volunteers\nTissue: Hydrogen breath tests\nExposure: Sucrose 50, 75 or 100 g; comparison with fructose alone\nRoute: Oral sugar solutions\nDuration: Breath sampling over 3-4 hours\nExposure scope: Human sucrose absorption\nLimits: No detected breath-hydrogen malabsorption in a small healthy cohort is not proof that every person tolerates every dose; CSID is a distinct condition.\nReference: Absorption capacity of fructose in healthy adults. Comparison with sucrose and its constituent monosaccharides. (1986). https://pubmed.ncbi.nlm.nih.gov/3781328/ DOI: 10.1136/gut.27.10.1161\nAccess: Primary abstract/metadata; unrecovered methods explicitly retained.","model_system":"Ten healthy adult volunteers","directness":"reported_statement","verification_status":"source_derived_draft","notes":"Exact original curation span, not a publisher quotation; provenance retained.","relationship":"supports","weight":1.0,"link_notes":"","source":{"id":"8e24ddf4-84ee-57b4-9fd8-093547432ece","stable_key":"import-c932089b-ebc9-5f39-b2e5-84af74f9f6d0","title":"Sucrose: mechanism of action and metabolic impact (2026-09-20)","document_type":"imported_text","citation_label":"Original AI-assisted source-specific sucrose curation with shared canonical claims retained by identity. Primary-study citations, negative findings, exposure details and limitations preserved. Not publisher full text.","file_path":"","sha256":"5e68ccbade7a80fc03778495756f0eeeeba5038cd10d5bef8e33cb1e93e4b044","revision_id":"6edb8ffc-11c5-5cd9-852c-85adb71165a8","review_status":"unverified_draft","notes":""}}],"relations":[],"conflicts":[],"corrections":[],"research":null}