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The authors describe the stabilisation as non-canonical, so the route from oxygen to HIF stability here is not the classical hydroxylase route.\nexposure: Hyperbaric oxygen in vitro and in vivo, with adenoviral stable HIF-1alpha delivery\nevidence_span: {\"source_cache\": \"artifacts/hbot-research/25532619.abstract.txt\", \"locator\": \"Indexed abstract; zero-based, end-exclusive Unicode character offsets\", \"file_sha256\": \"bb139ca47291f581e4d45523657f9f244734ce42a3e44c5e460671e58946a3ac\", \"start_char\": 0, \"end_char\": 1943, \"text_sha256\": \"bb139ca47291f581e4d45523657f9f244734ce42a3e44c5e460671e58946a3ac\"}\n[hbot-p25532619] Hyperbaric oxygen therapy activates hypoxia-inducible factor 1 (HIF-1), which contributes to improved wound healing in diabetic mice. 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