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(2018). https://pubmed.ncbi.nlm.nih.gov/30518682/ DOI: 10.1172/jci.insight.124486","comparator":null,"unit":null,"notes":"","entity":null},{"dimension":"tissue_or_cell_type","value_text":"Iron-deficiency anemia; n=1997 parent trial, n=185 substudy","comparator":null,"unit":null,"notes":"","entity":null},{"dimension":"trigger_kind","value_text":"machinery_impairment","comparator":null,"unit":null,"notes":"Imported condition classification; unverified.","entity":null}],"evidence":[{"id":"dce43940-1fd3-5dc6-97a5-0c28c5368da8","evidence_kind":"source_excerpt","locator":"Lines 1037-1048","start_line":1037,"end_line":1048,"excerpt":"### phosphorus-iron-pth\nPTH increased in the ferric-carboxymaltose-associated phosphate-wasting cascade.\nCondition category: machinery_impairment\nnutrient_topic: Phosphorus research collection; topical membership is not evidence of a direct dietary effect.\nplain_language: The parathyroid response added another hormone affecting renal phosphate handling.\norganism: Human\ntissue_or_cell_type: Iron-deficiency anemia; n=1997 parent trial, n=185 substudy\nexperimental_model: Randomized iron-formulation comparison with physiological substudy\nlimitations: Formulation-specific drug effect, not dietary iron. FGF23 was associated with the downstream changes; the exact reason the formulations differ was not settled.\nexposure: One trial course of ferric carboxymaltose or ferumoxytol; follow-up five weeks\nevidence_span: {\"source_cache\": \"artifacts/phosphorus-research/30518682.abstract.txt\", \"locator\": \"Primary indexed abstract; zero-based, end-exclusive Unicode character offsets\", \"file_sha256\": \"e1d37261355eedeff60d9715e7eb88b6718641ed868c5b3ab64fceaf62c15e6d\", \"start_char\": 0, \"end_char\": 2381, \"text_sha256\": \"e1d37261355eedeff60d9715e7eb88b6718641ed868c5b3ab64fceaf62c15e6d\"}\n[phosphorus-p30518682] Randomized trial of intravenous iron-induced hypophosphatemia. 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