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It measures the concentration range that matters rather than assuming it.","comparator":null,"unit":null,"notes":"","entity":null},{"dimension":"nutrient_topic","value_text":"GABA research collection; topical membership is not evidence of a direct clinical effect, and the sign of a GABA response depends on the chloride gradient of the cell it was measured in.","comparator":null,"unit":null,"notes":"","entity":{"slug":"gaba","display_name":"Gamma-aminobutyric acid","entity_type_key":"small_molecule"}},{"dimension":"organism","value_text":"Rat","comparator":null,"unit":null,"notes":"","entity":null},{"dimension":"plain_language","value_text":"These cells carry the kind of channel built for a steady background level rather than a synaptic pulse, and that background level slows them down.","comparator":null,"unit":null,"notes":"","entity":null},{"dimension":"primary_references","value_text":"[gb-p18954912] GABA, a natural immunomodulator of T lymphocytes. 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It measures the concentration range that matters rather than assuming it.\nexposure: GABA at nanomolar to micromolar concentrations, the range present around neurons\nevidence_span: {\"source_cache\": \"artifacts/gaba-research/18954912.abstract.txt\", \"locator\": \"Indexed abstract; zero-based, end-exclusive Unicode character offsets\", \"file_sha256\": \"3723b5b4b643817af252230d67dafbc0b5ca2deadb17cdbdbc9f340ddfc6a472\", \"start_char\": 0, \"end_char\": 728, \"text_sha256\": \"3723b5b4b643817af252230d67dafbc0b5ca2deadb17cdbdbc9f340ddfc6a472\"}\n[gb-p18954912] GABA, a natural immunomodulator of T lymphocytes. (2008). https://pubmed.ncbi.nlm.nih.gov/18954912/ DOI: 10.1016/j.jneuroim.2008.08.017","model_system":"Patch clamp and proliferation assays on encephalitogenic T cells at physiological GABA concentrations","directness":"author_interpretation","verification_status":"source_derived_draft","notes":"Exact curation-document quotation, not publisher quotation. 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