{"id":"1a93f15e-4ab3-5c80-93e3-0e19e30907a0","stable_key":"7edf94bb-95c8-5234-9161-9eb338bb9b36:boron-urine-intake-marker","predicate":"intake_correlates_with","statement":"Estimated intake correlated with 24-hour urinary boron excretion in vegans (r=0.79), omnivores (r=0.74) and less strongly in lacto-ovo-vegetarians (r=0.43).","claim_class":"observational","status":"source_derived_draft","evidence_grade":"ungraded","direction":"context_dependent","is_public":true,"mechanism_event_id":"3fb72a9e-e574-5cd5-b9ea-999b21e211f7","mechanism_event_label":"Urine boron tracked dietary exposure reasonably well in some groups; it did not diagnose deficiency.","subject":{"id":"5144a867-de17-599d-baec-68500e3d40bd","slug":"boron","display_name":"Boron","entity_type_key":"nutrient_element"},"object":{"id":"5ba7ded0-4d95-5ca2-ab42-da72fefef649","slug":"urinary-boron-excretion","display_name":"Urinary boron excretion","entity_type_key":"cellular_process"},"evidence_count":1,"mechanism_event":{"id":"3fb72a9e-e574-5cd5-b9ea-999b21e211f7","stable_key":"7edf94bb-95c8-5234-9161-9eb338bb9b36:boron-urine-intake-marker-event","event_type":"observed_intervention","label":"Urine boron tracked dietary exposure reasonably well in some groups; it did not diagnose deficiency.","description":"Estimated intake correlated with 24-hour urinary boron excretion in vegans (r=0.79), omnivores (r=0.74) and less strongly in lacto-ovo-vegetarians (r=0.43).","status":"provisional","compartment":null,"participants":[{"entity":{"id":"5144a867-de17-599d-baec-68500e3d40bd","slug":"boron","display_name":"Boron","entity_type_key":"nutrient_element"},"role":"subject","stoichiometry":null,"state_label":"","sequence_order":0,"notes":""},{"entity":{"id":"5ba7ded0-4d95-5ca2-ab42-da72fefef649","slug":"urinary-boron-excretion","display_name":"Urinary boron excretion","entity_type_key":"cellular_process"},"role":"target","stoichiometry":null,"state_label":"","sequence_order":1,"notes":""}]},"contexts":[{"dimension":"availability_state","value_text":"biomarker_context","comparator":null,"unit":null,"notes":"Imported condition classification; unverified.","entity":null},{"dimension":"evidence_span","value_text":"{\"source_cache\": \"artifacts/boron-research/42581205.abstract.txt\", \"locator\": \"Exact primary indexed abstract; zero-based, end-exclusive Unicode character offsets\", \"file_sha256\": \"616a276982b68c86769b127edd0b346732467698b8da80259d093b842708aa4b\", \"start_char\": 0, \"end_char\": 1953, \"text_sha256\": \"616a276982b68c86769b127edd0b346732467698b8da80259d093b842708aa4b\"}","comparator":null,"unit":null,"notes":"","entity":null},{"dimension":"experimental_model","value_text":"Cross-sectional diet records and 24-hour urine study; 89 adults","comparator":null,"unit":null,"notes":"","entity":null},{"dimension":"exposure","value_text":"28 lacto-ovo-vegetarians, 29 vegans and 32 omnivores in Germany","comparator":null,"unit":null,"notes":"","entity":null},{"dimension":"limitations","value_text":"Observational diet-pattern comparisons cannot show that boron causes potassium loss; shared food sources, intake estimation and renal handling can affect correlations. No diagnostic deficiency cutoff was validated.","comparator":null,"unit":null,"notes":"","entity":null},{"dimension":"nutrient_topic","value_text":"Boron research collection; topical membership is not evidence of a direct dietary effect.","comparator":null,"unit":null,"notes":"","entity":{"slug":"boron","display_name":"Boron","entity_type_key":"nutrient_element"}},{"dimension":"organism","value_text":"Human","comparator":null,"unit":null,"notes":"","entity":null},{"dimension":"plain_language","value_text":"Urine boron tracked dietary exposure reasonably well in some groups; it did not diagnose deficiency.","comparator":null,"unit":null,"notes":"","entity":null},{"dimension":"primary_references","value_text":"[boron-p42581205] Boron Intake and 24-hour Urinary Excretion in Long-term Omnivores, Vegetarians and Vegans: a Cross-sectional Study. (2026). https://pubmed.ncbi.nlm.nih.gov/42581205/ DOI: 10.1007/s12011-026-05297-x","comparator":null,"unit":null,"notes":"","entity":null},{"dimension":"tissue_or_cell_type","value_text":"Diet intake estimates and urine","comparator":null,"unit":null,"notes":"","entity":null},{"dimension":"trigger_kind","value_text":"biomarker_context","comparator":null,"unit":null,"notes":"Imported condition classification; unverified.","entity":null}],"evidence":[{"id":"fe90ddd5-667a-5b96-8788-5cedb5ca2693","evidence_kind":"source_excerpt","locator":"Lines 1119-1130","start_line":1119,"end_line":1130,"excerpt":"### boron-urine-intake-marker\nEstimated intake correlated with 24-hour urinary boron excretion in vegans (r=0.79), omnivores (r=0.74) and less strongly in lacto-ovo-vegetarians (r=0.43).\nCondition category: biomarker_context\nnutrient_topic: Boron research collection; topical membership is not evidence of a direct dietary effect.\nplain_language: Urine boron tracked dietary exposure reasonably well in some groups; it did not diagnose deficiency.\norganism: Human\ntissue_or_cell_type: Diet intake estimates and urine\nexperimental_model: Cross-sectional diet records and 24-hour urine study; 89 adults\nlimitations: Observational diet-pattern comparisons cannot show that boron causes potassium loss; shared food sources, intake estimation and renal handling can affect correlations. No diagnostic deficiency cutoff was validated.\nexposure: 28 lacto-ovo-vegetarians, 29 vegans and 32 omnivores in Germany\nevidence_span: {\"source_cache\": \"artifacts/boron-research/42581205.abstract.txt\", \"locator\": \"Exact primary indexed abstract; zero-based, end-exclusive Unicode character offsets\", \"file_sha256\": \"616a276982b68c86769b127edd0b346732467698b8da80259d093b842708aa4b\", \"start_char\": 0, \"end_char\": 1953, \"text_sha256\": \"616a276982b68c86769b127edd0b346732467698b8da80259d093b842708aa4b\"}\n[boron-p42581205] Boron Intake and 24-hour Urinary Excretion in Long-term Omnivores, Vegetarians and Vegans: a Cross-sectional Study. (2026). https://pubmed.ncbi.nlm.nih.gov/42581205/ DOI: 10.1007/s12011-026-05297-x","model_system":"Cross-sectional diet records and 24-hour urine study; 89 adults","directness":"author_interpretation","verification_status":"source_derived_draft","notes":"Exact curation-document quotation, not publisher quotation. Study references: [boron-p42581205] Boron Intake and 24-hour Urinary Excretion in Long-term Omnivores, Vegetarians and Vegans: a Cross-sectional Study. (2026). https://pubmed.ncbi.nlm.nih.gov/42581205/ DOI: 10.1007/s12011-026-05297-x","relationship":"supports","weight":1.0,"link_notes":"","source":{"id":"2d96c547-aeec-5d8b-9d31-1288da209f89","stable_key":"import-7edf94bb-95c8-5234-9161-9eb338bb9b36","title":"Boron: chemistry, nutrient interactions, low-intake studies and mechanistic uncertainties (2026-09-17)","document_type":"imported_text","citation_label":"AI-assisted literature curation; primary study URLs and scope retained in the document and extraction. Not publisher full text.","file_path":"","sha256":"0a32c1c5c70cfb4a378f6ace35cf5b75d90ed3065ada91b9f9f64015d603c8e3","revision_id":"38f316f2-4344-542e-a638-0ac5402f678d","review_status":"unverified_draft","notes":""}}],"relations":[],"conflicts":[],"corrections":[],"research":null}