{"id":"10cf3e52-aea5-522c-a995-7b2d6d217b41","stable_key":"22527305-af1f-536a-b419-7e73f08cc3ec:luteolin-microbial-end-product","predicate":"converts_to","statement":"Luteolin degradation by E. ramulus wK1 yielded dihydrocaffeic acid.","claim_class":"mechanistic","status":"source_derived_draft","evidence_grade":"ungraded","direction":"context_dependent","is_public":true,"mechanism_event_id":"70be1c84-ee69-585f-bb23-e5f32bf25721","mechanism_event_label":"A smaller phenolic acid emerges downstream.","subject":{"id":"5b74d97d-93aa-5a34-95f1-e90b14b2e7eb","slug":"eubacterium-ramulus-wk1","display_name":"Eubacterium ramulus strain wK1","entity_type_key":"organism"},"object":{"id":"9b2f330c-4038-548f-a827-71b8535f3874","slug":"dihydrocaffeic-acid","display_name":"Dihydrocaffeic acid / 3-(3,4-dihydroxyphenyl)propionic acid","entity_type_key":"small_molecule"},"evidence_count":1,"mechanism_event":{"id":"70be1c84-ee69-585f-bb23-e5f32bf25721","stable_key":"22527305-af1f-536a-b419-7e73f08cc3ec:luteolin-microbial-end-product-event","event_type":"observed_relationship","label":"A smaller phenolic acid emerges downstream.","description":"Luteolin degradation by E. ramulus wK1 yielded dihydrocaffeic acid.","status":"provisional","compartment":null,"participants":[{"entity":{"id":"5b74d97d-93aa-5a34-95f1-e90b14b2e7eb","slug":"eubacterium-ramulus-wk1","display_name":"Eubacterium ramulus strain wK1","entity_type_key":"organism"},"role":"subject","stoichiometry":null,"state_label":"","sequence_order":0,"notes":""},{"entity":{"id":"9b2f330c-4038-548f-a827-71b8535f3874","slug":"dihydrocaffeic-acid","display_name":"Dihydrocaffeic acid / 3-(3,4-dihydroxyphenyl)propionic acid","entity_type_key":"small_molecule"},"role":"target","stoichiometry":null,"state_label":"","sequence_order":1,"notes":""},{"entity":{"id":"80472c4b-ecc2-52e3-a766-f8463294774f","slug":"luteolin","display_name":"Luteolin / 3′,4′,5,7-tetrahydroxyflavone","entity_type_key":"small_molecule"},"role":"context_participant","stoichiometry":null,"state_label":"","sequence_order":2,"notes":""},{"entity":{"id":"7d1fbea5-a816-58de-b34d-15abe1d7da74","slug":"eriodictyol","display_name":"Eriodictyol","entity_type_key":"small_molecule"},"role":"context_participant","stoichiometry":null,"state_label":"","sequence_order":3,"notes":""}]},"contexts":[{"dimension":"evidence_access","value_text":"Primary abstract","comparator":null,"unit":null,"notes":"","entity":null},{"dimension":"experimental_model","value_text":"Anaerobic resting-cell fermentation.","comparator":null,"unit":null,"notes":"","entity":null},{"dimension":"limitations","value_text":"Intervening chalcones were proposed but not detected; do not invent confirmed enzyme steps.","comparator":null,"unit":null,"notes":"","entity":null},{"dimension":"nutrient_topic","value_text":"Luteolin collection; molecular form, preparation, species, exposure and manipulation remain explicit.","comparator":null,"unit":null,"notes":"","entity":{"slug":"luteolin","display_name":"Luteolin / 3′,4′,5,7-tetrahydroxyflavone","entity_type_key":"small_molecule"}},{"dimension":"plain_language","value_text":"A smaller phenolic acid emerges downstream.","comparator":null,"unit":null,"notes":"","entity":null},{"dimension":"primary_references","value_text":"Degradation of quercetin and luteolin by Eubacterium ramulus. · 2001 · https://pubmed.ncbi.nlm.nih.gov/11722907/ · DOI 10.1128/AEM.67.12.5558-5567.2001","comparator":null,"unit":null,"notes":"","entity":null}],"evidence":[{"id":"44f9b5a2-4e61-58e7-99cf-07eb3b51ffff","evidence_kind":"source_excerpt","locator":"Lines 260-266","start_line":260,"end_line":266,"excerpt":"## luteolin-microbial-end-product\nA smaller phenolic acid emerges downstream.\nLuteolin degradation by E. ramulus wK1 yielded dihydrocaffeic acid.\nModel: Anaerobic resting-cell fermentation.\nLimitations: Intervening chalcones were proposed but not detected; do not invent confirmed enzyme steps.\nEvidence access: Primary abstract\nDegradation of quercetin and luteolin by Eubacterium ramulus. · 2001 · https://pubmed.ncbi.nlm.nih.gov/11722907/ · DOI 10.1128/AEM.67.12.5558-5567.2001","model_system":"Anaerobic resting-cell fermentation.","directness":"reported_statement","verification_status":"source_derived_draft","notes":"Original curation paraphrase; evidence access and experimental limitations specified.","relationship":"supports","weight":1.0,"link_notes":"","source":{"id":"26337a08-5cee-5cee-900e-e6d3e26ac6e4","stable_key":"import-22527305-af1f-536a-b419-7e73f08cc3ec","title":"Luteolin: metabolism, immune signaling, redox chemistry and cross-nutrient mechanisms (2026-09-19)","document_type":"imported_text","citation_label":"AI-assisted research curation; primary-abstract references and experimental limitations individually identified. 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