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Findings are not diagnostic criteria; the paper’s factorial requirement estimates are not current recommended intakes.\nexposure: Three weeks at 2.59 mg Mn/day, then 39 days at 0.11 mg/day; repletion at 1.53 and 2.55 mg/day for five days each.\ncross_nutrient: Manganese handling and the measured downstream function.\nevidence_span: {\"source_cache\": \"artifacts/manganese-clinical-sources/friedman1987.abstract.txt\", \"locator\": \"Indexed primary abstract\", \"file_sha256\": \"ddc0b39d872786b905ca06d9b2470ebdf926ef42822e346f6bf003a180be4ba6\", \"start_char\": 0, \"end_char\": 1186, \"text_sha256\": \"ddc0b39d872786b905ca06d9b2470ebdf926ef42822e346f6bf003a180be4ba6\", \"text_characters\": 1186}\n[mn-clin-friedman1987] Manganese balance and clinical observations in young men fed a manganese-deficient diet. 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