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The mammalian relevance is the authors’ statement that the Tip60-steroid hormone axis is conserved, not a mammalian measurement.","comparator":null,"unit":null,"notes":"","entity":null},{"dimension":"nutrient_topic","value_text":"Acetic acid research collection; topical membership is not evidence of a direct clinical effect, and the ingested acid is recorded separately from the circulating acetate anion.","comparator":null,"unit":null,"notes":"","entity":{"slug":"acetic-acid","display_name":"Acetic acid","entity_type_key":"chemical_species"}},{"dimension":"organism","value_text":"Drosophila","comparator":null,"unit":null,"notes":"","entity":null},{"dimension":"plain_language","value_text":"In the fly, bacterial acetate switches on the gut immune pathway, and the same switch also controls how much fat the gut makes.","comparator":null,"unit":null,"notes":"","entity":null},{"dimension":"primary_references","value_text":"[acetate-p34107298] Microbiota-derived acetate activates intestinal innate immunity via the Tip60 histone acetyltransferase complex. 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The mammalian relevance is the authors’ statement that the Tip60-steroid hormone axis is conserved, not a mammalian measurement.\nexposure: Dietary acetate with disruption of a monocarboxylic acid transporter, of histone deacetylation, and of the Tip60 acetyltransferase\nevidence_span: {\"source_cache\": \"artifacts/acetate-research/34107298.abstract.txt\", \"locator\": \"Indexed abstract; zero-based, end-exclusive Unicode character offsets\", \"file_sha256\": \"4e5644412d174b2512ecf9cedea282b022d647b1b8a82f693a8f389da991425a\", \"start_char\": 0, \"end_char\": 1179, \"text_sha256\": \"4e5644412d174b2512ecf9cedea282b022d647b1b8a82f693a8f389da991425a\"}\n[acetate-p34107298] Microbiota-derived acetate activates intestinal innate immunity via the Tip60 histone acetyltransferase complex. 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