{"id":"05e13271-83ac-5a06-9569-3d5cecc378d8","stable_key":"1acdb1e8-2159-5c7f-b39f-0153ff8024ae:taurine-aging-monkey-health","predicate":"improves_measured_outcomes","statement":"Taurine treatment improved several measured health-related outcomes in monkeys in the 2023 study.","claim_class":"observational","status":"source_derived_draft","evidence_grade":"ungraded","direction":"context_dependent","is_public":true,"mechanism_event_id":"ea585bc7-a8d7-5986-91c1-76521f849ba9","mechanism_event_label":"The primate arm measured health outcomes rather than lifespan extension.","subject":{"id":"e423cd36-f183-522b-a5e4-5f9ef50eee7e","slug":"taurine","display_name":"Taurine","entity_type_key":"small_molecule"},"object":{"id":"d516015d-e6de-5779-bdfa-38e8524acaa5","slug":"monkey-taurine-healthspan","display_name":"Measured health outcomes in taurine-treated monkeys","entity_type_key":"cellular_process"},"evidence_count":1,"mechanism_event":{"id":"ea585bc7-a8d7-5986-91c1-76521f849ba9","stable_key":"1acdb1e8-2159-5c7f-b39f-0153ff8024ae:taurine-aging-monkey-health-event","event_type":"observed_relationship","label":"The primate arm measured health outcomes rather than lifespan extension.","description":"Taurine treatment improved several measured health-related outcomes in monkeys in the 2023 study.","status":"provisional","compartment":null,"participants":[{"entity":{"id":"e423cd36-f183-522b-a5e4-5f9ef50eee7e","slug":"taurine","display_name":"Taurine","entity_type_key":"small_molecule"},"role":"subject","stoichiometry":null,"state_label":"","sequence_order":0,"notes":""},{"entity":{"id":"d516015d-e6de-5779-bdfa-38e8524acaa5","slug":"monkey-taurine-healthspan","display_name":"Measured health outcomes in taurine-treated monkeys","entity_type_key":"cellular_process"},"role":"target","stoichiometry":null,"state_label":"","sequence_order":1,"notes":""}]},"contexts":[{"dimension":"evidence_access","value_text":"Primary abstract","comparator":null,"unit":null,"notes":"","entity":null},{"dimension":"experimental_model","value_text":"Nonhuman-primate supplementation arm.","comparator":null,"unit":null,"notes":"","entity":null},{"dimension":"limitations","value_text":"The study did not establish longer primate or human lifespan; health measures should not be relabeled survival.","comparator":null,"unit":null,"notes":"","entity":null},{"dimension":"nutrient_topic","value_text":"Taurine collection; molecular form, preparation, species, exposure and manipulation remain explicit.","comparator":null,"unit":null,"notes":"","entity":{"slug":"taurine","display_name":"Taurine","entity_type_key":"small_molecule"}},{"dimension":"plain_language","value_text":"The primate arm measured health outcomes rather than lifespan extension.","comparator":null,"unit":null,"notes":"","entity":null},{"dimension":"primary_references","value_text":"Taurine deficiency as a driver of aging. · 2023 · https://pubmed.ncbi.nlm.nih.gov/37289866/ · DOI 10.1126/science.abn9257","comparator":null,"unit":null,"notes":"","entity":null}],"evidence":[{"id":"26e79edd-5ff2-5c4d-8320-81ab09408ce9","evidence_kind":"source_excerpt","locator":"Lines 609-615","start_line":609,"end_line":615,"excerpt":"## taurine-aging-monkey-health\nThe primate arm measured health outcomes rather than lifespan extension.\nTaurine treatment improved several measured health-related outcomes in monkeys in the 2023 study.\nModel: Nonhuman-primate supplementation arm.\nLimitations: The study did not establish longer primate or human lifespan; health measures should not be relabeled survival.\nEvidence access: Primary abstract\nTaurine deficiency as a driver of aging. · 2023 · https://pubmed.ncbi.nlm.nih.gov/37289866/ · DOI 10.1126/science.abn9257","model_system":"Nonhuman-primate supplementation arm.","directness":"reported_statement","verification_status":"source_derived_draft","notes":"Original curation paraphrase; evidence access and experimental limitations specified.","relationship":"supports","weight":1.0,"link_notes":"","source":{"id":"dc8d9ab8-fdf9-5107-877c-336cf8005097","stable_key":"import-1acdb1e8-2159-5c7f-b39f-0153ff8024ae","title":"Taurine: synthesis, transport, mitochondrial decoding and nutrient interactions (2026-09-19)","document_type":"imported_text","citation_label":"AI-assisted research curation; primary-abstract references and experimental limitations individually identified. Not publisher full text.","file_path":"","sha256":"c6cb77619a374d9b1b04830032fdd3b33d269d160df5baba3778fad5adf57db5","revision_id":"cc45c491-cc6a-5426-ab72-d7c6d26c3614","review_status":"unverified_draft","notes":""}}],"relations":[],"conflicts":[],"corrections":[],"research":null}