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Cell-line species were not resolved in the retrieved abstract/figure evidence; no species-specific extension is asserted.","comparator":null,"unit":null,"notes":"","entity":null},{"dimension":"nutrient_topic","value_text":"Vitamin A research collection; topical membership is not evidence of a direct dietary effect.","comparator":null,"unit":null,"notes":"","entity":{"slug":"vitamin-a","display_name":"Vitamin A","entity_type_key":"chemical_species"}},{"dimension":"organism","value_text":"Mammalian transfected-cell preparations","comparator":null,"unit":null,"notes":"","entity":null},{"dimension":"outcome","value_text":"STRA6 accelerated retinol release from extracellular RBP in real-time assays.","comparator":null,"unit":null,"notes":"","entity":null},{"dimension":"plain_language","value_text":"The receptor unloads retinol from its blood carrier.","comparator":null,"unit":null,"notes":"","entity":null},{"dimension":"primary_references","value_text":"[va-kawaguchi-2011] Receptor-mediated cellular uptake mechanism that couples to intracellular storage (2011). https://pmc.ncbi.nlm.nih.gov/articles/PMC3199320/ DOI: 10.1021/cb200178w","comparator":null,"unit":null,"notes":"","entity":null},{"dimension":"tissue_or_cell_type","value_text":"Plasma membrane","comparator":null,"unit":null,"notes":"","entity":null},{"dimension":"transport_direction","value_text":"extracellular holo-RBP4 to membrane/cell","comparator":null,"unit":null,"notes":"","entity":null}],"evidence":[{"id":"8e7afe51-c775-57ef-9220-70af224bfd7c","evidence_kind":"source_excerpt","locator":"Lines 444-457","start_line":444,"end_line":457,"excerpt":"### va-stra6-retinol-release\nSTRA6 accelerated retinol release from extracellular RBP in real-time assays.\nCondition category: normal\nnutrient_topic: Vitamin A research collection; topical membership is not evidence of a direct dietary effect.\nplain_language: The receptor unloads retinol from its blood carrier.\norganism: Mammalian transfected-cell preparations\ntissue_or_cell_type: Plasma membrane\nexperimental_model: Transfected-cell radioretinol uptake and real-time retinol-release assays.\nlimitations: In vitro transport mechanism; no organism-wide flux estimate. Cell-line species were not resolved in the retrieved abstract/figure evidence; no species-specific extension is asserted.\nexposure: Retinol-loaded RBP and STRA6 expression.\noutcome: STRA6 accelerated retinol release from extracellular RBP in real-time assays.\nevidence_location: Abstract\ntransport_direction: extracellular holo-RBP4 to membrane/cell\n[va-kawaguchi-2011] Receptor-mediated cellular uptake mechanism that couples to intracellular storage (2011). https://pmc.ncbi.nlm.nih.gov/articles/PMC3199320/ DOI: 10.1021/cb200178w","model_system":"Transfected-cell radioretinol uptake and real-time retinol-release assays.","directness":"author_interpretation","verification_status":"source_derived_draft","notes":"Exact curation-document quotation, not publisher quotation. 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