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The reported 2000% increase is not a universal multiplier, therapeutic benefit or proof of long-term safety.\nexposure: 2 g curcumin with or without 20 mg piperine\nevidence_span: {\"source_cache\": \"artifacts/curcumin-research/9619120.abstract.txt\", \"locator\": \"Primary indexed abstract; zero-based, end-exclusive Unicode character offsets\", \"file_sha256\": \"e0eb4e2d68139e3b863853c46e30e52ad3bd67eaed1e6c4bbdefb278af10ee0b\", \"start_char\": 0, \"end_char\": 1316, \"text_sha256\": \"e0eb4e2d68139e3b863853c46e30e52ad3bd67eaed1e6c4bbdefb278af10ee0b\"}\n[curcumin-p9619120] Influence of piperine on the pharmacokinetics of curcumin in animals and human volunteers. (1998). https://pubmed.ncbi.nlm.nih.gov/9619120/ DOI: 10.1055/s-2006-957450","model_system":"Human single-dose pharmacokinetic comparison; separate rat experiments","directness":"author_interpretation","verification_status":"source_derived_draft","notes":"Exact curation-document quotation, not publisher quotation. 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